SDH-IN-3
SDH-IN-3 is a succinate dehydrogenase (SDH) inhibitor with an IC50 of 7.2 μg/mL. SDH-IN-3 exhibits excellent antifungal activities against Nigrospora oryzae with an EC50 of 1.9 μg/mL. SDH-IN-3 can be used for anti-infection research.
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- No. CAS: 2805297-11-2
- Fòrmula: C15H11F2N3OS
- Peso molecular:319.33
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
IC50 & Target
IC50: 7.2 mg/L succinate dehydrogenase (SDH)[1]
In Vitro
SDH-IN-3(Compound T6) (40 μg/mL; 6-7 days) has in vivo protective and curative activities against rice infected with N.oryzae mycelia 81.5% and 43.0%, respectively[1].
SDH-IN-3 (0-40 μg/mL; 14-80 hours) significantly inhibits the growth of N.oryzae mycelia and hinders spore germination and germ tube elongation[1].
SDH-IN-3(0-20 μg/mL; 12-36 hours) affects the mycelium membrane integrity of N.oryzae mycelia by increasing cell membrane permeability and causing peroxidation of cellular lipids[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2805297-11-2
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Peso molecular 319.33
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Fòrmula C15H11F2N3OS
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SMILES
O=C(NC1=CSC=C1)C2=C(C(F)F)N(C3=CC=CC=C3)N=C2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SDH-IN-3 Related Classifications
HY-155004 Related Classifications
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