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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
35 Results for "
complement component C5
" in MedChemExpress (MCE) Product Catalog:
Products (35)
35 Results for "complement component C5" in MCE Product Catalog:
7
7 Publications Verification
Referencia número: HY-P7695
Pureza: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; complement component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:
Mouse
Source:
E. coli
1
1 Cited Publications
Referencia número: HY-P700862
Pureza: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; complement component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:
Human
Source:
HEK293
1
1 Cited Publications
Referencia número: HY-P7864
Pureza: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; complement component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:
Human
Source:
E. coli
1
1 Cited Publications
Referencia número: HY-P81185
Synonyms: C5; C6; C7; C8; C9; complement component 5; complement component 6; complement component 7; complement component 8; complement component 9; MAC; Membrane attack complex; TCC; Terminal complement complex.
1
Referencia número: HY-P3502
No. CAS: 1841136-73-9
Synonyms: RA101495; RA3193
Target:
Áreas de investigación:
Referencia número: HY-NP004
Synonyms: CVF
Referencia número: HY-145720
No. CAS: 1639264-46-2
Synonyms: ALN-CC5
Áreas de investigación:
Cemdisiran (ALN-CC5) is an N-acetylgalactosamine-conjugated RNAi agent and also a complement component C5 inhibitor. Cemdisiran targets C5 mRNA, cleaves C5 mRNA via the endogenous RNA interference pathway, and inhibits the production of C5 protein in the liver. Cemdisiran exerts a dose-dependent inhibitory effect on total C5 concentrations in cynomolgus monkeys. When used in combination with Pozelimab (HY-P99786) in cynomolgus monkeys, Cemdisiran achieves a more sustained and complete inhibitory effect on complement activity. Cemdisiran can be used in the research of paroxysmal nocturnal hemoglobinuria and other complement-mediated diseases .
Referencia número: HY-148457
No. CAS: 1613641-69-2
Synonyms: Izervay
Target:
Áreas de investigación:
Avacincaptad pegol (Izervay) is a selective inhibitor targeting complement component C5, and is a pegylated ribonucleic acid aptamer. Avacincaptad pegol inhibits the cleavage of C5 into pro-inflammatory C5a and C5b, which forms the membrane attack complex (C5b-9), thereby reducing inflammatory cell recruitment and retinal cell damage. Avacincaptad pegol can slow the growth of geographic atrophy (GA) lesions and reduce the risk of persistent vision loss. Avacincaptad pegol can be used in research of geographic atrophy associated with age-related macular degeneration (AMD) and has been approved by the FDA .
Referencia número: HY-145720A
Pureza: 96.02%
Synonyms: ALN-CC5 sodium
Áreas de investigación:
Cemdisiran sodium (ALN-CC5 sodium) is an N-acetylgalactosamine-conjugated RNAi agent and also a complement component C5 inhibitor. Cemdisiran sodium targets C5 mRNA, cleaves C5 mRNA via the endogenous RNA interference pathway, and inhibits the production of C5 protein in the liver. Cemdisiran sodium exerts a dose-dependent inhibitory effect on total C5 concentrations in cynomolgus monkeys. When used in combination with Pozelimab (HY-P99786) in cynomolgus monkeys, Cemdisiran sodium achieves a more sustained and complete inhibitory effect on complement activity. Cemdisiran sodium can be used in the research of paroxysmal nocturnal hemoglobinuria and other complement-mediated diseases .
Referencia número: HY-P3502B
Target:
Áreas de investigación:
Zilucoplan (PEG2) is a Zilucoplan (HY-P3502) derivative, where the linker section replaces PEG24 by PEG2. Zilucoplan is a potent complement component 5 (C5) inhibitor .
Referencia número: HY-P3502A
Synonyms: RA101495 TFA; RA3193 TFA
Target:
Áreas de investigación:
Referencia número: HY-P99886
No. CAS: 219685-93-5
Synonyms: h5G1. 1-SC
Target:
Áreas de investigación:
Referencia número: HY-P704326
Pureza: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; complement component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:
Mouse
Source:
HEK293
Referencia número: HY-P705144
Pureza: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; complement component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:
Human
Source:
HEK293
Referencia número: HY-P704336
Pureza: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; complement component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:
Human
Source:
HEK293
Referencia número: HY-P705192
Pureza: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; complement component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:
Cynomolgus
Source:
HEK293
Referencia número: HY-P705283
Pureza: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; complement component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:
Rat
Source:
HEK293
Referencia número: HY-P704546
Pureza: ≥ 90%, as determined by SDS-PAGE.
Synonyms: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; complement component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:
Human
Source:
HEK293
Referencia número: HY-P704547
Pureza: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; complement component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
