Thiol-PEG2-acid
Based on 1 Customer Validation
Thiol-PEG2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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- Pureza: 96.0%
- No. CAS: 1379649-73-6
- Fòrmula: C7H14O4S
- Peso molecular:194.25
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Almacenamiento:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Ver todos los productos específicos de isoformas PROTAC Linkers
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Actividad biológica
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 1379649-73-6
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Appearance Liquid (Density: 1.173±0.06 g/cm3)
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Peso molecular 194.25
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Fòrmula C7H14O4S
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Color Colorless to light yellow
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SMILES
O=C(O)CCOCCOCCS
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
DMSO : 100 mg/mL (514.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (266 KB)
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SDS (620 KB)
- English - EN (620 KB)
- Français - FR (620 KB)
- Deutsch - DE (620 KB)
- Norwegian - NO (620 KB)
- Español - ES (620 KB)
- Swedish - SV (620 KB)
- Italian - IT (620 KB)
- Korean - KR (620 KB)
- Portuguese - PT (620 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.1480 mL | 25.7400 mL | 51.4801 mL | 128.7001 mL |
| 5 mM | 1.0296 mL | 5.1480 mL | 10.2960 mL | 25.7400 mL | |
| 10 mM | 0.5148 mL | 2.5740 mL | 5.1480 mL | 12.8700 mL | |
| 15 mM | 0.3432 mL | 1.7160 mL | 3.4320 mL | 8.5800 mL | |
| 20 mM | 0.2574 mL | 1.2870 mL | 2.5740 mL | 6.4350 mL | |
| 25 mM | 0.2059 mL | 1.0296 mL | 2.0592 mL | 5.1480 mL | |
| 30 mM | 0.1716 mL | 0.8580 mL | 1.7160 mL | 4.2900 mL | |
| 40 mM | 0.1287 mL | 0.6435 mL | 1.2870 mL | 3.2175 mL | |
| 50 mM | 0.1030 mL | 0.5148 mL | 1.0296 mL | 2.5740 mL | |
| 60 mM | 0.0858 mL | 0.4290 mL | 0.8580 mL | 2.1450 mL | |
| 80 mM | 0.0644 mL | 0.3218 mL | 0.6435 mL | 1.6088 mL | |
| 100 mM | 0.0515 mL | 0.2574 mL | 0.5148 mL | 1.2870 mL |
Thiol-PEG2-acid Related Classifications
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