U-56324
U-56324 is an orally effective ATP-sensitive potassium channel (KATP) inhibitor with an EC50 of 233 µM. U-56324 inhibits KATP channel activity in the plasma membrane of pancreatic B cells in a concentration-dependent and reversible manner, without affecting single-channel conductance. U-56324 can be used for research on type 2 diabetes and insulin secretion.
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- No. CAS: 75587-96-1
- Fòrmula: C11H15NO3
- Peso molecular:209.24
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
IC50 & Target
[1]|
KATP 233 μM (EC50) |
In Vitro
U-56324 (5-5000 μM; <10 seconds) directly, reversibly, and concentration-dependently inhibits K(ATP) channel activity in excised outside-out patches from mouse pancreatic B-cells with an EC50 of 233 μM, without affecting single channel conductance[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 75587-96-1
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Peso molecular 209.24
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Fòrmula C11H15NO3
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SMILES
O=C(C1=CC=C(CC(C)(C)C)NC1=O)O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
U-56324 Related Classifications
HY-187737 Related Classifications
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