TENM1 - teneurin transmembrane protein 1 Gene

Also Known as TNM; ODZ1; ODZ3; TEN1; TNM1; ten-1; TEN-M1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 10178

About TENM1

Cytogenetic location: Xq25 Genomic coordinates (GRCh38): X:124,375,903-125,204,312 (from NCBI)

This gene has 3 transcripts (splice variants), 208 orthologues, 4 paralogues and is associated with 1 phenotype. Broad expression in prostate (RPKM 2.1), brain (RPKM 2.0) and 17 other tissues.

Summary

The protein encoded by this gene belongs to the tenascin family and teneurin subfamily. It is expressed in the neurons and may function as a cellular signal transducer. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

TENM1 Products (3)

mRNA Protein Name
NM_001163278.2 NP_001156750.1 teneurin-1 isoform 1 precursor
NM_001163279.1 NP_001156751.1 teneurin-1 isoform 2 precursor
NM_014253.3 NP_055068.2 teneurin-1 isoform 3 precursor

TENM1 Protein Structure

Ten_N

Ten_N: Teneurin Intracellular Region (17 - 168)

Ten_N

Ten_N: Teneurin Intracellular Region (179 - 317)

hEGF

hEGF: Human growth factor-like EGF (740 - 752)

Tox-GHH

Tox-GHH: GHH signature containing HNH/Endo VII superfamily nuclease toxin (2640 - 2718)

  • 0
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  • 2500
  • 2725 a.a.
Protein Preferred Names Protein Names

teneurin-1

  • odz (odd Oz/ten-m, Drosophila) homolog 3

Related Diseases

Diseases Alias
Anosmia, Isolated Congenital

  • ANIC

  • Isolated Congenital Anosmia

  • Anosmia, Congenital

  • Congenital Anosmia
Anal Margin Carcinoma

  • Carcinoma Of Anal Margin

  • Perianal Skin Carcinoma
Anal Canal Carcinoma

  • Anal Canal Cancer

  • Anal Canal And Perianal Gland Carcinoma

  • Carcinoma Of The Anal Canal

  • Carcinoma Of Anal Canal
Microphthalmia

  • Microphthalmos

  • Isolated Anophthalmia-Microphthalmia Syndrome

  • Isolated Microphthalmia-Anophthalmia-Coloboma

  • Simple Microphthalmos

  • Clinical Anophthalmia

  • Isolated Anophthalmia - Microphthalmia

  • Isolated Pure Microphthalmia

  • Mac Spectrum

  • Microphthalmia-Anophthalmia-Coloboma Spectrum

  • Primitive Anophthalmia

  • Globe Of Eye Small

  • Small Eyeball

  • Hypoplasia Of Eye

  • Isolated Nanophthalmos

  • Rudimentary Eye

  • Dysplasia Of Eye
Cerebral Palsy

  • Infantile Cerebral Palsy

  • Mixed Cerebral Palsy

  • Palsy Cerebral

  • Palsy, Cerebral

  • Cerebral Palsy, Mixed
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14362 TENM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22854 Tenm1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29368 Tenm1 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris TENM1 VGNC VGNC:47246
Mus musculus TENM1 MGD MGI:1345185
Felis catus TENM1 VGNC VGNC:68620
Rattus norvegicus TENM1 RGD RGD:1561678
Macaca mulatta TENM1 VGNC VGNC:79969
Bos taurus TENM1 VGNC VGNC:35741
Others TENM1 NCBI