Traf3ip2 - TRAF3 interacting protein 2 Gene

Also Known as Act1; CIKS

Species: Mus musculus

Gene Type: protein coding
Gene ID: 103213

Summary

Enables signaling receptor binding activity and ubiquitin protein Ligase activity. Involved in several processes, including cell surface receptor signaling pathway; hematopoietic or lymphoid organ development; and leukocyte homeostasis. Acts upstream of or within B cell apoptotic process and humoral immune response. Is active in cytoplasmic vesicle and nucleus. Used to study Sjogren's syndrome; atopic dermatitis; and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in chronic mucocutaneous candidiasis and psoriasis 13. Orthologous to human TRAF3IP2 (TRAF3 interacting protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Traf3ip2 Products (1)

mRNA Protein Name
NM_134000.3 NP_598761.2 E3 ubiquitin ligase TRAF3IP2
Protein Preferred Names Protein Names

E3 ubiquitin ligase TRAF3IP2

adapter protein CIKS

  • E3 ubiquitin-protein ligase CIKS

  • connection to IKK and SAPK/JNK

  • nuclear factor NF-kappa-B activator 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14971 TRAF3IP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22078 Traf3ip2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28597 Traf3ip2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Traf3ip2 NCBI NCBI:10758