Pmch - pro-melanin-concentrating hormone Gene

Also Known as A230109K23Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 110312

Summary

This gene encodes a preproprotein that is cleaved to produce three mature peptides: melanin concentrating hormone, neuropeptide-glutamic acid-isoleucine (NEI), and neuropeptide-glycine-glutamic acid (NGE). The proprotein is processed differently depending on the tissue where it is expressed. Melanin concentrating hormone is involved in the regulation of food intake, energy homeostasis, and sleep-wake behavior. Disruption of this gene is associated with resistance to diet-induced obesity. [provided by RefSeq, May 2013]

Pmch Products (1)

mRNA Protein Name
NM_029971.2 NP_084247.1 pro-MCH preproprotein

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in feeding behavior IMP
IMP: Inferred from mutant phenotype
11867747 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
8724342 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pro-MCH

  • neuropeptide-glutamic acid-isoleucine (NEI)

  • neuropeptide-glycine-glutamic acid (NGE)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10759 PMCH Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22282 Pmch Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28805 Pmch Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pmch NCBI NCBI:5367