Cd37 - CD37 antigen Gene

Also Known as Tspan26

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12493

Summary

Acts upstream of or within several processes, including defense response to protozoan; negative regulation of myeloid dendritic cell activation; and positive regulation of immunoglobulin production. Predicted to be located in immunological synapse. Predicted to be integral component of plasma membrane. Is expressed in thymus primordium. Orthologous to human CD37 (CD37 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd37 Products (3)

mRNA Protein Name
NM_001290802.1 NP_001277731.1 leukocyte antigen CD37 isoform 1
NM_001290804.1 NP_001277733.1 leukocyte antigen CD37 isoform 2
NM_007645.4 NP_031671.1 leukocyte antigen CD37 isoform 3

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence Références Source
acts upstream of T cell proliferation IGI
IGI: Inferred from genetic interaction
20709950 MGI
acts upstream of or within defense response to protozoan IGI
IGI: Inferred from genetic interaction
20709950 MGI
acts upstream of immunoglobulin production IMP
IMP: Inferred from mutant phenotype
10891477 MGI
acts upstream of or within negative regulation of T cell proliferation IGI
IGI: Inferred from genetic interaction
20709950 MGI
acts upstream of or within negative regulation of myeloid dendritic cell activation IGI
IGI: Inferred from genetic interaction
20709950 MGI
acts upstream of or within positive regulation of immunoglobulin production IMP
IMP: Inferred from mutant phenotype
10891477 MGI
acts upstream of or within regulation of defense response to virus IGI
IGI: Inferred from genetic interaction
20709950 MGI
acts upstream of or within regulation of humoral immune response IMP
IMP: Inferred from mutant phenotype
10891477 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

leukocyte antigen CD37

Recombinant Cd37 Proteins

Cat. No. Nom du produit Accession Pureté
HY-P75418 CD37 Protein, Mouse (HEK293, hFc) Q61470 (R112-N241) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (4)
Cat. No. Nom du produit Effect
Pureté Phase
HY-132260 Naratuximab emtansine Inducer 98.52% Phase 2
HY-P99674 Ivicentamab Inhibitor 99.82% Phase 2
HY-P99707 Lilotomab Inducer 98.99% Phase 2
HY-P990317 AGS-67E Inhibitor 99.46% Phase 1

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS02238 CD37 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17365 Cd37 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23819 Cd37 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (3)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-P99374 Naratuximab 99.9% Unkown
HY-P991523 BI-836826 Inducer / Unkown
HY-P991912 PSB107 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cd37 NCBI NCBI:951