Lilotomab
Based on 1 Customer Validation
Lilotomab (HH1) is a murine anti-CD37 monoclonal antibody. Lilotomab reduces clonogenic survival. Lilotomab shows anti-tumor activity.
For research use only. We do not sell to patients.
- Purity: 98.99%
- CAS No.: 1453362-55-4
- Molecular Weight:145.24 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Human IgG1 kappa
Human
TSPAN26/CD37
Lilotomab (0-40 µg/mL; 12 days) reduces the clonogenic survival of DOHH2 and Ramos cells[1].
Lilotomab (40 µg/mL; 18 h) induces slight apoptosis in DOHH2 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Ramos, DOHH2, Rec-1 cells
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Concentration:40 µg/mL
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Incubation Time:18 h
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Result:Induced apoptosis in DOHH2 cells.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:SCID mice (DOHH2 cell xenografts)[1]
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Dosage:0.5 mg/kg
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Administration:I.v.; once
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Result:Inhibited tumor growth and increased mouse survival.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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IgG1-kappa
ELISA, FACS, Functional assay
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Flow Cytometry analysis of Raji cells labelling TSPAN26/CD37 (red) with Lilotomab (anti-TSPAN26/CD37) (HY-P99707). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG1 kappa (HY-P99001). Black-Unlabelled control, cells without incubation with primary antibody.
Chemical Information
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CAS No. 1453362-55-4
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Appearance Liquid
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Molecular Weight 145.24 kDa
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Color Colorless to light yellow
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SMILES
[Lilotomab]
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Synonyms
HH1
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (259 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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