Cd8b1 - CD8 antigen, beta chain 1 Gene

Also Known as Cd8b; Ly-3; Ly-C; Lyt-3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12526

Summary

Predicted to enable MHC class I protein binding activity and coreceptor activity. Predicted to be involved in regulation of immune response. Predicted to act upstream of or within adaptive immune response. Located in external side of plasma membrane. Is expressed in several structures, including alimentary system; endocrine gland; hemolymphoid system gland; liver and biliary system; and reproductive system. Orthologous to several human genes including CD8b (CD8b molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd8b1 Products (1)

mRNA Protein Name
NM_009858.3 NP_033988.1 T-cell surface glycoprotein CD8 beta chain precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12215456 MGI
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
14568922 MGI
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
1673361 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
22081144 MGI
part of receptor complex IPI
IPI: Inferred from physical interaction
22081144 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

T-cell surface glycoprotein CD8 beta chain

  • T-cell membrane glycoprotein Ly-3

  • T-cell surface glycoprotein Lyt-3

  • lymphocyte antigen 3

Recombinant Cd8b1 Proteins

Cat. No. Product Name Accession Purity
HY-P74259 CD8A-CD8B Heterodimer Protein, Mouse (HEK293, Flag-His) P01731 (K28-Y196)&P10300 (L22-T175) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02276 CD8B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25091 Cd8b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown