Dnajc5 - DnaJ heat shock protein family (Hsp40) member C5 Gene
Also Known as Csp; 2610314I24Rik
Species: Mus musculus
Summary
Predicted to enable ATP-dependent protein binding activity. Involved in chaperone-mediated protein folding and regulation of synaptic vesicle cycle. Acts upstream of or within negative regulation of neuron apoptotic process. Located in neuromuscular junction and synaptic vesicle. Is active in presynapse. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 4B. Orthologous to human DNAJC5 (DnaJ heat shock protein family (HSP40) member C5). [provided by Alliance of Genome Resources, Apr 2022]
Dnajc5 Products (3)
| mRNA | Protein | Name |
|---|---|---|
| NM_001271584.1 | NP_001258513.1 | dnaJ homolog subfamily C member 5 |
| NM_001271585.1 | NP_001258514.1 | dnaJ homolog subfamily C member 5 |
| NM_016775.3 | NP_058055.1 | dnaJ homolog subfamily C member 5 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
25253725 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in chaperone-mediated protein folding |
IDA
IDA: Inferred from direct assay
|
21151134 | MGI |
| involved in chaperone-mediated protein folding |
IEP
IEP: Inferred from expression pattern
|
21151134 | MGI |
| involved in chaperone-mediated protein folding |
IMP
IMP: Inferred from mutant phenotype
|
21151134 | MGI |
| acts upstream of or within negative regulation of neuron apoptotic process |
IGI
IGI: Inferred from genetic interaction
|
16269331 | MGI |
| acts upstream of neuron apoptotic process |
IGI
IGI: Inferred from genetic interaction
|
16269331 | MGI |
| involved in regulation of synaptic vesicle cycle |
IDA
IDA: Inferred from direct assay
|
22500637 | MGI |
| involved in regulation of synaptic vesicle cycle |
IEP
IEP: Inferred from expression pattern
|
22500637 | MGI |
| involved in regulation of synaptic vesicle cycle |
IMP
IMP: Inferred from mutant phenotype
|
22500637 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| is active in neuromuscular junction |
IDA
IDA: Inferred from direct assay
|
22500637 | MGI |
| is active in neuromuscular junction |
IEP
IEP: Inferred from expression pattern
|
22500637 | MGI |
| is active in neuromuscular junction |
IMP
IMP: Inferred from mutant phenotype
|
22500637 | MGI |
| is active in presynapse |
IDA
IDA: Inferred from direct assay
|
21151134 | MGI |
| is active in presynapse |
IEP
IEP: Inferred from expression pattern
|
21151134 | MGI |
| is active in presynapse |
IMP
IMP: Inferred from mutant phenotype
|
21151134 | MGI |
| located in synaptic vesicle |
IDA
IDA: Inferred from direct assay
|
16407767 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
dnaJ homolog subfamily C member 5 |
|