Eef1a2 - eukaryotic translation elongation factor 1 alpha 2 Gene

Also Known as S1; STN; wst; Eef1a; EEF1AL; wasted; EF-1-alpha-2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 13628

Summary

Enables translation elongation factor activity. Acts upstream of or within positive regulation of apoptotic process and translational elongation. Located in cytoplasm. Part of eukaryotic translation elongation factor 1 complex. Is active in synapse. Is expressed in several structures, including central nervous system; eye; genitourinary system; gut; and integumental system. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability 38; developmental and epileptic encephalopathy 33; and ovarian Cancer. Orthologous to human EEF1A2 (eukaryotic translation elongation factor 1 alpha 2). [provided by Alliance of Genome Resources, Apr 2022]

Eef1a2 Products (1)

mRNA Protein Name
NM_007906.3 NP_031932.1 elongation factor 1-alpha 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables translation elongation factor activity IDA
IDA: Inferred from direct assay
9588196 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of apoptotic process IDA
IDA: Inferred from direct assay
11724805 MGI
acts upstream of or within translational elongation IDA
IDA: Inferred from direct assay
9588196 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
15013623 MGI
part of eukaryotic translation elongation factor 1 complex IDA
IDA: Inferred from direct assay
9588196 MGI
is active in synapse EXP
EXP: Inferred from Experiment
16452087 MGI
is active in synapse IDA
IDA: Inferred from direct assay
16452087 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

elongation factor 1-alpha 2

  • eukaryotic elongation factor 1 A-2

  • statin-S1

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-16050 Plitidepsin Inhibitor 99.94% Unkown

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-120118 Metarrestin Inhibitor 99.90% Phase 1

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-179370 EEF1A2-IN-1 / Unkown
HY-RS04175 EEF1A2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04176 EEF1B2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19059 Eef1b2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21848 Eef1a2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24785 Eef1a1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25549 Eef1b2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Eef1a2 NCBI NCBI:1917