APOOL - apolipoprotein O like Gene

Also Known as Mic27; CXorf33; FAM121A; MICOS27; UNQ8193

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 139322

About APOOL

Cytogenetic location: Xq21.1 Genomic coordinates (GRCh38): X:85,003,877-85,093,315 (from NCBI)

This gene has 1 transcript (splice variant), 209 orthologues and 1 paralogue. Ubiquitous expression in brain (RPKM 7.7), thyroid (RPKM 6.2) and 25 other tissues.

Summary

This gene encodes a protein which contains an Apolipoprotein O superfamily domain. This domain is found on proteins in circulating lipoprotein complexes. [provided by RefSeq, Sep 2011]

APOOL Products (1)

mRNA Protein Name
NM_198450.6 NP_940852.3 MICOS complex subunit MIC27 precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25764979 GOA
Cellular Component GO Annotation Evidence References Source
part of MICOS complex IDA
IDA: Inferred from direct assay
25781180 GOA
located in mitochondrion IDA
IDA: Inferred from direct assay
25781180 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

APOOL Protein Structure

ApoO

ApoO: Apolipoprotein O (27 - 179)

  • 0
  • 100
  • 200
  • 268 a.a.
Protein Preferred Names Protein Names

MICOS complex subunit MIC27

  • AAIR8193

Related Diseases

Diseases Alias
Combined Oxidative Phosphorylation Deficiency 37

  • COXPD37
Deafness, X-Linked 7

  • X-Linked External Auditory Canal Atresia-Dilated Internal Auditory Canal-Facial Dysmorphism Syndrome

  • DFNX7

  • X-Linked Deafness 7

  • Deafness, X-Linked, 7
Barth Syndrome

  • 3-Methylglutaconic Aciduria Type 2

  • BTHS

  • Cardioskeletal Myopathy With Neutropenia And Abnormal Mitochondria

  • Mga Type Ii

  • Mga2

  • Mgca2

  • Mga Type 2

  • 3-Methylglutaconic Aciduria Type Ii

  • 3-Methylglutaconic Aciduria, Type Ii

  • Mga, Type Ii

  • 3-Methylglutaconicaciduria Type 2

  • 3-Methylglutaconicaciduria Type Ii

  • Taz Defect

  • 3 Methylglutaconic Aciduria, Type Ii

  • Dnajc19 Defect

  • Cardioskeletal Myopathy-Neutropenia Syndrome

  • X-Linked Cardioskeletal Myopathy And Neutropenia

  • 3-Alpha-Methylglutaconic Aciduria Type 2

  • Agm2

  • Cardioskeletal Myopathy-Neutropenia

  • Invm

  • Left Ventricular Non-Compaction Isolated X-Linked

  • Non-Compaction Of Left Ventricular Myocardium Isolated X-Linked

  • Agammaglobulinemia 2, Autosomal Recessive
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00862 APOOL Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus APOOL RGD RGD:1549725
Mus musculus APOOL MGD MGI:1915367
Canis familiaris APOOL VGNC VGNC:38009
Macaca mulatta APOOL VGNC VGNC:97734
Bos taurus APOOL VGNC VGNC:26036