Elmo1 - engulfment and cell motility 1 Gene

Also Known as CED-12; 6330578D22Rik; C230095H21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 140580

Summary

Predicted to enable SH3 domain binding activity. Predicted to contribute to guanyl-nucleotide exchange factor activity. Acts upstream of or within actin filament-based process and phagocytosis. Part of guanyl-nucleotide exchange factor complex. Is expressed in several structures, including genitourinary system; hemolymphoid system gland; nervous system; retina; and vibrissa. Orthologous to human ELMO1 (engulfment and cell motility 1). [provided by Alliance of Genome Resources, Apr 2022]

Elmo1 Products (2)

mRNA Protein Name
NM_080288.2 NP_525027.1 engulfment and cell motility protein 1 isoform 3
NM_198093.3 NP_932761.1 engulfment and cell motility protein 1 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15102471 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within actin filament-based process IDA
IDA: Inferred from direct assay
11595183 MGI
acts upstream of or within phagocytosis IDA
IDA: Inferred from direct assay
11595183 MGI
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
29949770 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
29949770 MGI
part of guanyl-nucleotide exchange factor complex IDA
IDA: Inferred from direct assay
11595183 MGI
is active in postsynapse IDA
IDA: Inferred from direct assay
29949770 MGI
is active in postsynapse IMP
IMP: Inferred from mutant phenotype
29949770 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

engulfment and cell motility protein 1

  • engulfment and cell motility 1, ced-12 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04311 ELMO1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22485 Elmo1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29008 Elmo1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Elmo1 NCBI NCBI:9844