F7 - coagulation factor VII Gene

Also Known as Cf7; FVII

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14068

Summary

This gene encodes a vitamin K-dependent serine protease that plays a critical role in the extrinsic pathway of blood coagulation. Upon contact with tissue factor III (TF III), the encoded protein forms an activated complex termed TF-FVIIa that initiates the coagulation cascade involving Other coagulation factors, ultimately resulting in a fibrin clot. Complete lack of the encoded protein in mice results in in perinatal lethality due to bleeding from normal blood vessels. [provided by RefSeq, Apr 2015]

F7 Products (1)

mRNA Protein Name
NM_010172.5 NP_034302.2 coagulation factor VII preproprotein

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within blood coagulation IMP
IMP: Inferred from mutant phenotype
9384381 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

coagulation factor VII

  • serum prothrombin conversion accelerator

Recombinant F7 Proteins

Cat. No. Product Name Accession Purity
HY-P73045 Coagulation Factor VII/F7 Protein, Mouse (CHO, His) Q542C2 (V25-L446) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (17)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-113437A 1,2-Dipalmitoyl-sn-glycerol 3-phosphate sodium 98.0% Unkown
HY-122678 LQZ-7F 97.44% Unkown
HY-W250541 Fmoc-Gly-NH-CH2-O-Cyclopropane-CH2COOH 98.10% Unkown
HY-156095 F7H Inhibitor 99.95% Unkown
HY-113437 1,2-Dipalmitoyl-sn-glycerol 3-phosphate / Unkown
HY-113437AS 1,2-Dipalmitoyl-sn-glycerol 3-phosphate-d62 sodium 99.0% Unkown
HY-W079257 Desamino lenalidomide-7-F ≥98.0% Unkown
HY-146033 HPV18-IN-1 Inhibitor / Unkown
HY-148696A Gly-Cyclopropane-Exatecan Inhibitor / Unkown
HY-RS04116 E2F7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04645 F7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-46572 Benzyl 2-cyclopropyl-2-hydroxyacetate 98.43% Unkown
HY-RS16932 F7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18926 E2f7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23375 F7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25416 E2f7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W460228 Desamino lenalidomide-4-F-7-Br 99.90% Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991703 Mocertatug Inhibitor 98% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens F7 NCBI NCBI:2155