Olr1 - oxidized low density lipoprotein receptor 1 Gene

Also Known as LOX-1; Oldr1; Oldlr1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 140914

Summary

Predicted to enable identical protein binding activity and low-density lipoprotein particle receptor activity. Involved in several processes, including leukocyte cell-cell adhesion; lipoprotein metabolic process; and response to hydrogen peroxide. Predicted to be located in nucleoplasm. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Biomarker of end stage renal disease and hypertension. Human ortholog(s) of this gene implicated in cerebral amyloid angiopathy; coronary artery disease; and myocardial infarction. Orthologous to human OLR1 (oxidized low density lipoprotein receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Olr1 Products (2)

mRNA Protein Name
NM_133306.2 NP_579840.2 oxidized low-density lipoprotein receptor 1
NM_133306.2 NP_579840.2 oxidized low-density lipoprotein receptor 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in leukocyte cell-cell adhesion IMP
IMP: Inferred from mutant phenotype
12538855 RGD
involved in lipoprotein metabolic process IMP
IMP: Inferred from mutant phenotype
12435393 RGD
involved in negative regulation of miRNA transcription IMP
IMP: Inferred from mutant phenotype
28108289 RGD
involved in response to hydrogen peroxide IEP
IEP: Inferred from expression pattern
16055083 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

oxidized low-density lipoprotein receptor 1

  • Lectin-like oxidized low-density lipoprotein receptor-1

  • lectin-like oxLDL receptor 1

  • lectin-like oxidized LDL receptor 1

  • lectin-like oxidized low-density lipoprotein receptor

  • lectin-type oxidized LDL receptor 1

  • ox-LDL receptor 1

  • oxidised low density

Recombinant Olr1 Proteins

Cat. No. Product Name Accession Purity
HY-P73835 LOX-1/OLR1 Protein, Rat (HEK293, His) O70156 (L60-Q364) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P73836 LOX-1/OLR1 Protein, Rat (HEK293, Fc) O70156 (L60-Q364) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16991 Olr1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09780 OLR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23434 Olr1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Olr1 NCBI NCBI:4973