Fgf1 - fibroblast growth factor 1 Gene

Also Known as Fam; Fgfa; Dffrx; Fgf-1; Fgf2b

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14164

Summary

Predicted to enable several functions, including HSP70 protein binding activity; S100 protein binding activity; and signaling receptor binding activity. Acts upstream of or within several processes, including organ induction; positive regulation of epithelial cell proliferation; and positive regulation of nitrogen compound metabolic process. Located in extracellular matrix and extracellular space. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in brain ischemia; cleft lip; myocardial infarction; schizophrenia; and urinary bladder Cancer. Orthologous to human FGF1 (Fibroblast Growth Factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Fgf1 Products (1)

mRNA Protein Name
NM_010197.3 NP_034327.1 fibroblast growth factor 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16263090 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of epithelial cell proliferation IDA
IDA: Inferred from direct assay
17187775 MGI
acts upstream of or within lung development IDA
IDA: Inferred from direct assay
15576401 MGI
acts upstream of or within organ induction IDA
IDA: Inferred from direct assay
15576401 MGI
acts upstream of or within positive regulation of epithelial cell proliferation IDA
IDA: Inferred from direct assay
17187775 MGI
acts upstream of or within positive regulation of protein phosphorylation IDA
IDA: Inferred from direct assay
15800000 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
8898217 MGI
Cellular Component GO Annotation Evidence References Source
located in extracellular matrix IDA
IDA: Inferred from direct assay
15381701 MGI
located in extracellular region IDA
IDA: Inferred from direct assay
19233122 MGI
located in extracellular space IDA
IDA: Inferred from direct assay
15576401 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fibroblast growth factor 1

  • HBGF-1

  • aFGF

  • acidic fibroblast growth factor

  • fibroblast growth factor 1 (acidic)

  • fibroblast growth factor 2b

  • heparin-binding growth factor 1

Recombinant Fgf1 Proteins

Cat. No. Product Name Accession Purity
HY-P7065 FGF-1 Protein, Mouse P61148 (F16-D155) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P700282 FGF-1 Protein, Mouse (N-His) P61148 (F16-D155) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-100434 PD-161570 Inhibitor 98.78% Unkown
HY-126436D Poly-L-ornithine hydrochloride (MW 15000-30000) / Unkown
HY-149352 DG1 Inhibitor / Unkown
HY-P10955 Ac-AAVALLPAVLLALLAPVAD-CHO TFA Inhibitor / Unkown
HY-RS04886 FGF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174712 Human FGF1 mRNA / Unkown
HY-RS16610 Fgf1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23045 Fgf1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fgf1 NCBI NCBI:2246