FGF1 - fibroblast growth factor 1 Gene

Also Known as AFGF; ECGF; FGFA; ECGFA; ECGFB; FGF-1; HBGF1; HBGF-1; GLIO703; ECGF-beta; FGF-alpha

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 2246

About FGF1

Cytogenetic location: 5q31.3 Genomic coordinates (GRCh38): 5:142,592,178-142,698,070 (from NCBI)

This gene has 16 transcripts (splice variants), 128 orthologues and 21 paralogues. Biased expression in brain (RPKM 36.0), kidney (RPKM 21.0) and 4 other tissues.

Summary

The protein encoded by this gene is a member of the Fibroblast Growth Factor (FGF) family. FGF Family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Jan 2009]

FGF1 Products (27)

mRNA	Protein	Name
NM_000800.5	NP_000791.1	fibroblast growth factor 1 isoform 1 precursor
NM_001144892.3	NP_001138364.1	fibroblast growth factor 1 isoform 1 precursor
NM_001144934.2	NP_001138406.1	fibroblast growth factor 1 isoform 1 precursor
NM_001144935.2	NP_001138407.1	fibroblast growth factor 1 isoform 1 precursor
NM_001257205.1	NP_001244134.1	fibroblast growth factor 1 isoform 1 precursor
NM_001257206.2	NP_001244135.1	fibroblast growth factor 1 isoform 4 precursor
NM_001257207.2	NP_001244136.1	fibroblast growth factor 1 isoform 1 precursor
NM_001257208.2	NP_001244137.1	fibroblast growth factor 1 isoform 1 precursor
NM_001257209.1	NP_001244138.1	fibroblast growth factor 1 isoform 1 precursor
NM_001257210.2	NP_001244139.1	fibroblast growth factor 1 isoform 1 precursor
NM_001257211.2	NP_001244140.1	fibroblast growth factor 1 isoform 4 precursor
NM_001257212.2	NP_001244141.1	fibroblast growth factor 1 isoform 4 precursor
NM_001354951.2	NP_001341880.1	fibroblast growth factor 1 isoform 1 precursor
NM_001354952.2	NP_001341881.1	fibroblast growth factor 1 isoform 1 precursor
NM_001354953.2	NP_001341882.1	fibroblast growth factor 1 isoform 1 precursor
NM_001354954.2	NP_001341883.1	fibroblast growth factor 1 isoform 1 precursor
NM_001354955.2	NP_001341884.1	fibroblast growth factor 1 isoform 1 precursor
NM_001354956.2	NP_001341885.1	fibroblast growth factor 1 isoform 1 precursor
NM_001354957.2	NP_001341886.1	fibroblast growth factor 1 isoform 4
NM_001354958.2	NP_001341887.1	fibroblast growth factor 1 isoform 4
NM_001354959.2	NP_001341888.1	fibroblast growth factor 1 isoform 2
NM_001354961.2	NP_001341890.1	fibroblast growth factor 1 isoform 2
NM_001354962.2	NP_001341891.1	fibroblast growth factor 1 isoform 2
NM_001354963.2	NP_001341892.1	fibroblast growth factor 1 isoform 2
NM_001354964.2	NP_001341893.1	fibroblast growth factor 1 isoform 2
NM_033136.4	NP_149127.1	fibroblast growth factor 1 isoform 2 precursor
NM_033137.4	NP_149128.1	fibroblast growth factor 1 isoform 3

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Verweise	Source
enables S100 protein binding	IPI IPI: Inferred from physical interaction	11432880	GOA
enables fibroblast growth factor receptor binding	IMP IMP: Inferred from mutant phenotype	18441324	GOA
enables fibroblast growth factor receptor binding	IPI IPI: Inferred from physical interaction	10830168	GOA
enables growth factor activity	IDA IDA: Inferred from direct assay	20145243	GOA
enables heparin binding	IDA IDA: Inferred from direct assay	20145243	GOA
enables heparin binding	IMP IMP: Inferred from mutant phenotype	18441324	GOA
enables integrin binding	IDA IDA: Inferred from direct assay	18441324	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	10618369	GOA

Biological Process GO Annotation	Evidence	Verweise	Source
involved in activation of protein kinase B activity	IMP IMP: Inferred from mutant phenotype	18441324	GOA
involved in branch elongation involved in ureteric bud branching	IDA IDA: Inferred from direct assay	11731227	GOA
involved in cellular response to heat	IDA IDA: Inferred from direct assay	12746488	GOA
involved in fibroblast growth factor receptor signaling pathway	IDA IDA: Inferred from direct assay	20145243	GOA
acts upstream of or within fibroblast growth factor receptor signaling pathway	IGI IGI: Inferred from genetic interaction	8663044	GOA
involved in fibroblast growth factor receptor signaling pathway	IMP IMP: Inferred from mutant phenotype	18441324	GOA
acts upstream of or within fibroblast growth factor receptor signaling pathway	IPI IPI: Inferred from physical interaction	10830168	GOA
involved in mesonephric epithelium development	IDA IDA: Inferred from direct assay	11731227	GOA
involved in positive regulation of ERK1 and ERK2 cascade	IMP IMP: Inferred from mutant phenotype	18441324	GOA
involved in positive regulation of MAP kinase activity	IDA IDA: Inferred from direct assay	16756958	GOA
involved in positive regulation of angiogenesis	IDA IDA: Inferred from direct assay	20145243	GOA
involved in positive regulation of cell division	IDA IDA: Inferred from direct assay	20145243	GOA
involved in positive regulation of cell migration	IDA IDA: Inferred from direct assay	20145243	GOA
involved in positive regulation of cell migration	IMP IMP: Inferred from mutant phenotype	18441324	GOA
acts upstream of or within positive regulation of cell population proliferation	IGI IGI: Inferred from genetic interaction	8663044	GOA
involved in positive regulation of cell population proliferation	IMP IMP: Inferred from mutant phenotype	18441324	GOA
involved in positive regulation of cholesterol biosynthetic process	IDA IDA: Inferred from direct assay	19229075	GOA
involved in positive regulation of endothelial cell migration	IMP IMP: Inferred from mutant phenotype	23469107	GOA
involved in positive regulation of intracellular signal transduction	IDA IDA: Inferred from direct assay	19229075	GOA
involved in positive regulation of sprouting angiogenesis	IMP IMP: Inferred from mutant phenotype	23469107	GOA
involved in positive regulation of transcription by RNA polymerase II	IDA IDA: Inferred from direct assay	19229075	GOA
involved in regulation of endothelial cell chemotaxis to fibroblast growth factor	IDA IDA: Inferred from direct assay	16756958	GOA
involved in regulation of endothelial tube morphogenesis	IMP IMP: Inferred from mutant phenotype	23469107	GOA
involved in wound healing	IDA IDA: Inferred from direct assay	16756958	GOA

Cellular Component GO Annotation	Evidence	Verweise	Source
located in cytosol	IDA IDA: Inferred from direct assay	12746488	GOA
located in extracellular region	IDA IDA: Inferred from direct assay	12746488	GOA
located in extracellular space	IDA IDA: Inferred from direct assay	18400376	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FGF1 Protein Structure

FGF

0
100
155 a.a.

Protein Preferred Names	Protein Names
fibroblast growth factor 1	beta-endothelial cell growth factor

FGF1 Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Verweise
Intra	FGF1	P05230	FGFR1	Homo sapiens	P11362	Anti Tag CoIP	33961781
Intra	FGF1	P05230	FGFR1	Homo sapiens	P11362	SPR	18441324
Intra	FGF1	P05230	FGFR2	Homo sapiens	P21802	PLA	25241761
Intra	FGF1	P05230	FGFR2	Homo sapiens	P21802	Anti Tag CoIP	33961781
Intra	FGF1	P05230	FGFR3	Homo sapiens	P22607	SPR	14732692
Intra	FGF1	P05230	FGFR3	Homo sapiens	P22607	X-Ray Diffraction	14732692
Intra	FGF1	P05230	VBP1	Homo sapiens	P61758	Y2H Array	32296183
Intra	FGF1	P05230	VBP1	Homo sapiens	P61758	Validated Y2H	32296183
Intra	FGF1	P05230	VBP1	Homo sapiens	P61758	Y2H Prey Pooling	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant FGF1 Proteins

Art. -Nr.	Produktname	Accession	Reinheit
HY-P7001	FGF-1 Protein, Human	P05230-1 (F16-D155)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P700053AF	Animal-Free FGF-1 Protein, Human (His)	P05230-1 (F16-D155)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P700289	FGF-1 Protein, Human (154a.a)	P05230-1 (A2-D155)	≥ 95%, as determined by reducing SDS-PAGE.

FGF1 Antibodies

Art. -Nr.	Produktname	Anwendung	Reactivity
HY-P81685	FGF1 Antibody (YA1430)	WB, IHC-P	Human, Mouse, Rat

Related Diseases

Diseases	Alias
Common Peroneal Nerve Lesion	Lesion Of Lateral Popliteal Nerve Fibular Neuropathy
Overnutrition
Sclerosteosis	Cortical Hyperostosis With Syndactyly Sost Cortical Hyperostosis-Syndactyly Syndrome
Pleomorphic Adenoma	Mixed Tumor Of The Salivary Gland Adenoma Pleomorphic Adenoma, Pleomorphic Mixed Salivary Gland Tumor Mixed Tumor, Not Otherwise Specified
Pancreatic Adenocarcinoma	Adenocarcinoma Of The Pancreas Adenocarcinoma Of Pancreas Pancreas Adenocarcinoma Malignant Exocrine Neoplasm Primary Pancreatic Adenocarcinoma Adenocarcinoma Of Islet Cell Of Pancreas Islet Cell Adenocarcinoma Of Unspecified Site Mixed Adenocarcinoma Islet Cell With Exocrine Of Unspecified Site
Arteriosclerosis	Arteriosclerotic Vascular Disease
Spinal Stenosis	Lumbar Spinal Stenosis Cervical Spinal Stenosis Spinal Stenosis Of Lumbar Region Spinal Stenosis In Cervical Region Spinal Canal Stenosis
Endometrial Cancer	Endometrial Carcinoma Endometrial Neoplasm Malignant Neoplasm Of Endometrium Endometrioid Carcinoma Endometrial Neoplasms Carcinoma, Endometrioid Endometrial Cancer, Familial Endometrial Carcinoma, Somatic Endometrial Cancer, Susceptibility To Endometrial Ca Malignant Endometrial Neoplasm Neoplasm Of Endometrium Primary Malignant Neoplasm Of Endometrium Tumor Of Endometrium Carcinoma Of The Endometrium Endometrioid Carcinoma Of Female Reproductive System ENDMC Carcinoma Endometrioid Endometrial Cancers Cancer, Endometrial Uterine Corpus Cancer
Bladder Cancer	Urinary Bladder Cancer Bladder Carcinoma Urinary Bladder Carcinoma Bladder Neoplasm Bladder Tumor Cancer, Bladder Malignant Neoplasm Of Urinary Bladder Carcinoma Of Bladder Bladder Cancer, Somatic Tumor Of The Bladder Carcinoma Of Urinary Bladder Bladder Carcinoma Urinary Cancer Of The Urinary Bladder Cancer, Urinary Bladder Malignant Bladder Neoplasm Malignant Bladder Tumor Neoplasm Of The Bladder Neoplasm Of The Urinary Bladder Tumor Of The Urinary Bladder Urinary Bladder Neoplasm BLC Urothelial Carcinoma Of The Bladder Bladder Tumors Urinary Bladder Neoplasms Bladder Cancer Nos Vesical Cancer Nos Malignant Neoplasm Of Bladder, Part Unspecified Malignant Tumour Of Urinary Bladder Primary Malignant Neoplasm Of Bladder
Vitreoretinopathy, Neovascular Inflammatory	Proliferative Vitreoretinopathy Adniv Autosomal Dominant Neovascular Inflammatory Vitreoretinopathy VRNI Pvr Neovascular Inflammatory Vitreoretinopathy Vitreoretinopathy, Neovascular Inflammatory, Autosomal Dominant Retinitis Proliferans Neovascular Inflammatory Vitreoretinopathy Autosomal Dominant Vitreoretinopathy Proliferative Vitreoretinopathy, Proliferative Proliferative Vitreo-Retinopathy
Crouzon Syndrome	Crouzon Craniofacial Dysostosis Craniofacial Dysostosis Cfd1 Craniofacial Dysostosis Type 1 Crouzon Disease Crouzon'S Disease Craniofacial Dysostosis, Type I Craniofacial Dysarthrosis Craniofacial Dysostosis Syndrome CS Craniofacial Dysostosis Type I Vogt Cephalosyndactyly
Craniosynostosis	Premature Closure Of Cranial Sutures Craniostenosis Craniosynostosis Syndrome Cso Craniosynostoses Congenital Ossification Of Cranial Sutures Congenital Ossification Of Sutures Of Skull Craniostosis Imperfect Fusion Of Skull Congenital Imperfect Closure Skull Imperfect Closure Skull Premature Closure Cranium Sutures Deficiency Of Craniofacial Axis
Beare-Stevenson Cutis Gyrata Syndrome	Cutis Gyrata Syndrome Of Beare And Stevenson Beare-Stevenson Syndrome BSTVS Cutis Gyrata-Acanthosis Nigricans-Craniosynostosis Syndrome Beare Stevenson Syndrome Cutis Gyrata - Acanthosis Nigricans - Craniosynostosis Cutis Gyrata Syndrome Of Beare-Stevenson
Lacrimoauriculodentodigital Syndrome	Ladd Syndrome Levy-Hollister Syndrome Lacrimo-Auriculo-Dento-Digital Syndrome LADD Lacrimoauriculodento-Digital Syndrome Levy Hollister Syndrome Lard Syndrome Lacrimoauriculoradiodental Syndrome LADDS Congenital Duodenal Obstruction Due To Malrotation Of Intestine
Breast Cancer	Breast Carcinoma Male Breast Cancer Breast Cancer, Familial Malignant Neoplasm Of Breast Breast Cancer, Susceptibility To Breast Cancer, Early-Onset Malignant Tumor Of Breast Carcinoma Of Male Breast Breast Cancer, Invasive Ductal Breast Cancer, Protection Against Breast Cancer, Somatic Breast Cancer, Male Breast Cancer, Lobular, Somatic Breast Tumor Mammary Cancer Mammary Tumor Malignant Neoplasm Of Male Breast Mammary Carcinoma Male Breast Carcinoma Familial Cancer Of Breast Invasive Ductal Breast Carcinoma Breast Cancer Susceptibility Breast Cancer, Male, Susceptibility To Breast Cancer, Early-Onset, Susceptibility To Malignant Tumor Of The Breast Mammary Neoplasm Primary Breast Cancer Neoplasm Of Male Breast Carcinoma Of Breast Breast Cancer In Men Familial Breast Cancer Cancer Of Breast BC Breast Cancer Familial Breast Cancer Familial Male Breast Cancer, Familial Male Breast Male Carcinoma Breast Neoplasms Breast Neoplasms, Male Mammary Tumors Mammary Carcinomas Cancer, Breast Cancer, Breast, Susceptibility Invasive Breast Ductal Carcinoma Breast Neoplasm Susceptibility To Breast Cancer Mammary Neoplasms Animal Mammary Neoplasms Primary Malignant Neoplasm Of Breast Infiltrating Ductal Carcinoma Of Breast Infiltrating Duct Carcinoma Of Unspecified Site Infiltrating Ductular Carcinoma Of Unspecified Site Invasive Breast Carcinoma Of No Special Type Microinvasive Carcinoma Of Breast Carcinoma With Apocrine Differentiation
Osteoglophonic Dysplasia	Osteoglophonic Dwarfism OGD Fairbank-Keats Syndrome Osteoglosphonic Dysplasia Dysplasia, Osteoglophonic
Thanatophoric Dysplasia, Type I	Thanatophoric Dysplasia Thanatophoric Dwarfism Thanatophoric Dysplasia Type 1 TD1 Td Thanatophoric Short Stature Thanatophoric Dwarfism Type 1 Thanatophoric Dysplasia Type I Platyspondylic Lethal Skeletal Dysplasia, San Diego Type Lethal Short-Limbed Platyspondylic Dwarfism, San Diego Type Skeletal Dysplasia, San Diego Type Plsd San Diego Type Thanatophoric Dwarfism 1 Dwarfism Thanatophoric Dwarf, Thanatophoric Thanatophoric Dysplasia 1 Lethal Short-Limbed Platyspondylic Dwarfism San Diego Type Platyspondylic Lethal Skeletal Dysplasia San Diego Type Thanatophoric Dwarf Thanatophoric Dwarfism Or Short Stature Thanatophoric Dwarfism Syndrome Td - [Thanatophoric Dwarfism]
Pancreatic Cancer	Pancreatic Carcinoma Carcinoma Of Pancreas Familial Pancreatic Carcinoma Pancreatic Neoplasm Pancreatic Carcinoma, Familial Malignant Neoplasm Of Pancreas Pancreatic Acinar Carcinoma Pancreatic Tumor Familial Pancreatic Cancer Neoplasm Of The Pancreas Cancer Of The Pancreas Pancreatic Carcinoma, Somatic Pancreatic Cancer, Somatic Ca Body Of Pancreas Ca Head Of Pancreas Ca Tail Of Pancreas Malignant Neoplasm Of Body Of Pancreas Malignant Neoplasm Of Head Of Pancreas Malignant Neoplasm Of Tail Of Pancreas Pancreas Neoplasm Exocrine Cancer Exocrine Pancreas Carcinoma Hereditary Pancreatic Cancer Hereditary Pancreatic Carcinoma PNCA Pancreatic Cancer, Susceptibility To Carcinoma Of Head Of Pancreas Pancreatic Neoplasms Pancreatic Tumors Cancer, Pancreatic Cancer Of Pancreas Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site
Hypochondroplasia	HCH Hypochondrodysplasia Chondrogenesis Imperfecta Hypochondroplastic Dwarfism Hypochondroplastic Short Stature
Jackson-Weiss Syndrome	JWS Craniosynostosis, Midfacial Hypoplasia, And Foot Abnormalities Craniosynostosis-Midfacial Hypoplasia-Foot Abnormalities Syndrome Craniosynostosis-Midfacial Hypoplasia-Foot Abnormalities
Mononeuritis Of Lower Limb
Subungual Glomus Tumor	Subungual Glomus Tumour
Hypogonadotropic Hypogonadism 2 With Or Without Anosmia	Kallmann Syndrome 2 Kal2 HH2 Hypogonadism, Hypogonadotropic, Type 2 With/Without Anosmia
Decubitus Ulcer	Pressure Ulcer Pressure Sores Pressure Ulcers Bedsore Decubitus Ulcer Decubitus Ulcer Any Site
Prostate Cancer	Prostate Carcinoma Prostate Cancer, Familial Prostate Neoplasm Prostate Cancer, Somatic Prostate Cancer, Susceptibility To Prostatic Cancer Prostatic Neoplasms Hereditary Prostate Cancer Prostatic Neoplasm Cancer Of Prostate Carcinoma Of Prostate Familial Prostate Cancer Familial Prostate Carcinoma Malignant Tumor Of Prostate Malignant Neoplasm Of Prostate Prostate Cancer, Familial, Susceptibility To Malignant Tumor Of The Prostate Ngp - New Growth Of Prostate Tumor Of The Prostate Prostate Cancer, Hereditary Cancer Of The Prostate Malignant Neoplasm Of The Prostate Prostatic Carcinoma PC Prca Cancer, Prostate Malignant Prostatic Tumour Malignant Tumour Of Prostate Primary Prostate Cancer Primary Malignant Neoplasm Of Prostate Prostate Gland Cancer
Gastric Cancer	Stomach Cancer Gastric Carcinoma Stomach Carcinoma Gastric Cancer, Somatic Gastric Neoplasm Carcinoma Of Stomach Stomach Neoplasms Malignant Neoplasm Of Stomach Gastric Cancer Risk After H. Pylori Infection Cancer Of The Stomach Adult Stomach Cancer Adult Stomach Carcinoma GASC Gastric Cancer Intestinal Gastric Cancers Gastric Carcinomas Cancer, Gastric Stomach Neoplasm Malignant Neoplasm Of Body Of Stomach Malignant Tumor Of Lesser Curve Of Stomach Gastrocarcinoma Of Unspecified Site Leather Bottle Stomach Carcinoma Of Fundus Of Stomach Cancer Of Fundus Of Stomach Primary Malignant Neoplasm Of Body Of Stomach Cancer Of Body Of Stomach Primary Malignant Neoplasm Of Pyloric Antrum Pyloric Antrum Cancer Malignant Tumour Of Stomach
Ovarian Cancer	Ovarian Carcinoma Ovarian Neoplasm Malignant Tumour Of Ovary Cancer Of The Ovary Epithelial Ovarian Cancer Neoplasm Of Ovary Ovarian Neoplasms Ovarian Cancers Malignant Neoplasm Of Ovary Primary Malignant Neoplasm Of Ovary Ovarian Cancer, Somatic Malignant Ovarian Tumor Ovary Neoplasm Primary Ovarian Cancer Tumor Of The Ovary Malignant Neoplasm Of The Ovary Malignant Tumor Of The Ovary Ovarian Malignant Tumor OC Ovarian Carcinomas Cancer, Ovarian Cancer Of Ovary Ovary Cancer Ca Ovary
Lipoprotein Quantitative Trait Locus	Coronary Artery Disease Coronary Artery Anomaly Coronary Artery Disease, Susceptibility To Myocardial Ischemia Congenital Anomaly Of Coronary Artery Coronary Arteriosclerosis Coronary Disease Coronary Heart Disease Coronary Artery Disorder LPAQTL Lpa Deficiency, Congenital Coronary Artery Abnormality Coronary Artery Anomaly, Congenital Chd Coronary Syndrome Congenital Malformations Of Coronary Vessels Malformation Of Coronary Vessels Congenital Coronary Artery Anomaly Congenital Coronary Artery Deformity Congenital Coronary Artery Disorder Abnormal Coronary Artery Congenital Coronary Artery Malposition Congenital Coronary Disease Congenital Anomaly Of Coronary Arteries
Cleft Palate, Isolated	Cleft Palate Isolated Cleft Palate CPI Cp Palatoschisis Cleft Palate Isolated Uranostaphyloschisis Congenital Fissure Of Palate Cleft Of Secondary Palate
Kallmann Syndrome	Hypogonadism With Anosmia Kallman'S Syndrome Anosmic Hypogonadism Anosmic Idiopathic Hypogonadotropic Hypogonadism Hypogonadotropic Hypogonadism And Anosmia Hypogonadotropic Hypogonadism-Anosmia Syndrome Olfacto-Genital Pathological Sequence Familial Hypogonadism With Anosmia Kallman Syndrome Dysplasia Olfactogenitalis Of De Morsier Kallmann'S Syndrome Congenital Hypogonadotropic Hypogonadism With Anosmia
Osteochondrodysplasia	Skeletal Dysplasia Chondrodystrophy Congenital Anomaly Of Cartilage Osteochondrodysplasias Cartilage Development Disorder Osteochondrodysplasia Syndrome Dysplasia, Skeletal Mucopolysaccharidosis Iv
Amyotrophic Lateral Sclerosis 1	Amyotrophic Lateral Sclerosis ALS Lou Gehrig Disease Amyotrophic Lateral Sclerosis Type 1 Charcot Disease ALS1 Amyotrophic Lateral Sclerosis, Susceptibility To Fals Lou Gehrig'S Disease Mnd Motor Neuron Disease Familial Amyotrophic Lateral Sclerosis Amyotrophic Lateral Sclerosis 1, Familial Amyotrophic Lateral Sclerosis 1, Autosomal Dominant Motor Neuron Disease, Bulbar Motor Neurone Disease Amyotrophic Lateral Sclerosis With Dementia Dementia With Amyotrophic Lateral Sclerosis Motor Neuron Disease, Amyotrophic Lateral Sclerosis Sclerosis, Lateral, Amyotrophic Sclerosis, Lateral, Amyotrophic, Type 1 Amyotrophic Sclerosis Als - [Amyotrophic Lateral Sclerosis] Wasting Palsy Amyotrophic Paralysis Amyotrophy Lateral Sclerosis Wasting Paralysis Spinal Progressive Amyotrophy Progressive Atrophic Paralysis
Alzheimer Disease, Familial, 1	Alzheimer Disease Alzheimer'S Disease Presenile And Senile Dementia AD1 Alzheimer Disease, Susceptibility To Alzheimer Disease, Late-Onset, Susceptibility To Alzheimer Disease 1, Familial AD Familial Alzheimer Disease Alzheimer Disease, Late-Onset Alzheimers Dementia Alzheimer Dementia Alzheimer Sclerosis Alzheimer Syndrome Alzheimer-Type Dementia Dat Primary Senile Degenerative Dementia Sdat Alzheimer Disease 1 Autosomal Dominant Alzheimer Disease Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy Late Onset Alzheimer Disease Alzheimers Disease Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy Late-Onset Alzheimers Disease Alzheimer'S Disease Pathway Kegg Dementia Due To Alzheimer'S Disease Alzheimer Disease Type 1 Alzheimers

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)

Art. -Nr.	Produktname	Wirkung	Reinheit	Rare Diseases
HY-100434	PD-161570	Inhibitor	98.78%	Unkown
HY-126436D	Poly-L-ornithine hydrochloride (MW 15000-30000)		/	Unkown
HY-149352	DG1	Inhibitor	/	Unkown
HY-P10955	Ac-AAVALLPAVLLALLAPVAD-CHO TFA	Inhibitor	/	Unkown
HY-RS04886	FGF1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-174712	Human FGF1 mRNA		/	Unkown
HY-RS16610	Fgf1 Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS23045	Fgf1 Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	FGF1	RGD	RGD:2605
Mus musculus	FGF1	MGD	MGI:95515
Canis familiaris	FGF1	VGNC	VGNC:52134
Felis catus	FGF1	VGNC	VGNC:102206
Macaca mulatta	FGF1	VGNC	VGNC:110464
Bos taurus	FGF1	VGNC	VGNC:28970
Others	FGF1	NCBI