Fgf7 - fibroblast growth factor 7 Gene

Also Known as Kgf; Fgf5b

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14178

Summary

Predicted to enable heparin binding activity; receptor ligand activity; and type 2 Fibroblast Growth Factor receptor binding activity. Involved in positive regulation of transcription, DNA-templated. Acts upstream of or within morphogenesis of an epithelium; positive regulation of epithelial cell proliferation; and regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling. Located in Golgi apparatus and extracellular region. Is expressed in several structures, including alimentary system; brain; embryo mesenchyme; genitourinary system; and integumental system. Orthologous to human FGF7 (Fibroblast Growth Factor 7). [provided by Alliance of Genome Resources, Apr 2022]

Fgf7 Products (1)

mRNA Protein Name
NM_008008.4 NP_032034.1 fibroblast growth factor 7 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15806171 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within branching involved in salivary gland morphogenesis IDA
IDA: Inferred from direct assay
18559345 MGI
acts upstream of endothelial cell proliferation IDA
IDA: Inferred from direct assay
14697353 MGI
acts upstream of epithelial cell proliferation IDA
IDA: Inferred from direct assay
17187775 MGI
acts upstream of or within hair follicle morphogenesis IMP
IMP: Inferred from mutant phenotype
11098134 MGI
acts upstream of myoblast proliferation IDA
IDA: Inferred from direct assay
15806171 MGI
acts upstream of myoblast proliferation IGI
IGI: Inferred from genetic interaction
15806171 MGI
involved in positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
17394208 MGI
acts upstream of or within positive regulation of endothelial cell proliferation IDA
IDA: Inferred from direct assay
14697353 MGI
acts upstream of or within positive regulation of epithelial cell proliferation IDA
IDA: Inferred from direct assay
17187775 MGI
acts upstream of or within positive regulation of myoblast proliferation IDA
IDA: Inferred from direct assay
15806171 MGI
acts upstream of or within positive regulation of myoblast proliferation IGI
IGI: Inferred from genetic interaction
15806171 MGI
acts upstream of or within regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling IDA
IDA: Inferred from direct assay
18559345 MGI
involved in regulation of synapse maturation IDA
IDA: Inferred from direct assay
20505669 MGI
involved in regulation of synapse maturation IMP
IMP: Inferred from mutant phenotype
20505669 MGI
Cellular Component GO Annotation Evidence References Source
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
20505669 MGI
is active in GABA-ergic synapse IMP
IMP: Inferred from mutant phenotype
20505669 MGI
located in Golgi apparatus IDA
IDA: Inferred from direct assay
12837279 MGI
located in extracellular region IDA
IDA: Inferred from direct assay
12837279 MGI
is active in postsynapse IDA
IDA: Inferred from direct assay
20505669 MGI
is active in postsynapse IMP
IMP: Inferred from mutant phenotype
20505669 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fibroblast growth factor 7

  • FGF-7

  • HBGF-7

  • Keratinocyte growth factor

  • fibroblast growth factor 5b

  • heparin-binding growth factor 7

Recombinant Fgf7 Proteins

Cat. No. Product Name Accession Purity
HY-P7176 KGF/FGF-7 Protein, Mouse P36363 (C32-T194) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P11162 FGF7p 99.34% Unkown
HY-RS04905 FGF7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174693 Human FGF7 mRNA / Unkown
HY-174711 Human FGF10 mRNA / Unkown
HY-RS16714 Fgf7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23149 Fgf7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991584 HuGAL-FR21 Inhibitor 97.80% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fgf7 NCBI NCBI:2252