Gm2a - GM2 ganglioside activator protein Gene
Also Known as SAP-3; GM2-AP
Species: Mus musculus
Summary
Enables beta-N-acetylhexosaminidase activity and enzyme activator activity. Acts upstream of or within several processes, including ganglioside catabolic process; lipid storage; and neuromuscular process controlling balance. Located in mitochondrion. Is expressed in several structures, including back skin; central nervous system; genitourinary system; hemolymphoid system; and retina. Used to study GM2 gangliosidosis, AB variant. Human ortholog(s) of this gene implicated in GM2 gangliosidosis and GM2 gangliosidosis, AB variant. Orthologous to human GM2A (GM2 ganglioside activator). [provided by Alliance of Genome Resources, Apr 2022]
Gm2a Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_010299.3 | NP_034429.1 | ganglioside GM2 activator precursor |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
ganglioside GM2 activator |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS29483 | GM2A Cattle Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS05513 | GM2A Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS18134 | Gm2a Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS24609 | Gm2a Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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