DES - desmin Gene

Also Known as CSM1; CSM2; CDCD3; LGMD1D; LGMD1E; LGMD2R

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 1674

About DES

Cytogenetic location: 2q35 Genomic coordinates (GRCh38): 2:219,418,377-219,426,734 (from NCBI)

This gene has 5 transcripts (splice variants), 276 orthologues, 68 paralogues and is associated with 8 phenotypes. Biased expression in heart (RPKM 2605.8), esophagus (RPKM 953.7) and 6 other tissues.

Summary

This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each Other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq, Jul 2008]

DES Products (7)

mRNA	Protein	Name
NM_001382708.1	NP_001369637.1	desmin isoform 2
NM_001382709.1	NP_001369638.1	desmin isoform 3
NM_001382710.1	NP_001369639.1	desmin isoform 4
NM_001382711.1	NP_001369640.1	desmin isoform 5
NM_001382712.1	NP_001369641.1	desmin isoform 6
NM_001382713.1	NP_001369642.1	desmin isoform 7
NM_001927.4	NP_001918.3	desmin isoform 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables cytoskeletal protein binding	IPI IPI: Inferred from physical interaction	11309420	GOA
enables identical protein binding	IPI IPI: Inferred from physical interaction	21135508	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	11353857	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in intermediate filament organization	IMP IMP: Inferred from mutant phenotype	24200904	GOA

Cellular Component GO Annotation	Evidence	References	Source
located in Z disc	IDA IDA: Inferred from direct assay	9415431	GOA
located in cardiac myofibril	IDA IDA: Inferred from direct assay	25771144	GOA
located in intercalated disc	IDA IDA: Inferred from direct assay	24200904	GOA
located in sarcolemma	IDA IDA: Inferred from direct assay	25394388	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

DES Protein Structure

Filament_head

Filament

0
100
200
300
400
470 a.a.

Protein Preferred Names	Protein Names
desmin	cardiomyopathy, dilated 1F (autosomal dominant)

DES Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	DES	P17661	PIH1D2	Homo sapiens	Q8WWB5	Y2H Array	32296183
Intra	DES	P17661	PIH1D2	Homo sapiens	Q8WWB5	Y2H Prey Pooling	32296183
Intra	DES	P17661	PIH1D2	Homo sapiens	Q8WWB5	Validated Y2H	32296183
Intra	DES	P17661	KRT37	Homo sapiens	O76014	Y2H Prey Pooling	32296183
Intra	DES	P17661	KRT37	Homo sapiens	O76014	Y2H Array	32296183
Intra	DES	P17661	KRT33B	Homo sapiens	Q14525	Y2H Array	32296183
Intra	DES	P17661	KRT33B	Homo sapiens	Q14525	Validated Y2H	32296183
Intra	DES	P17661	KRT33B	Homo sapiens	Q14525	Y2H Prey Pooling	32296183
Intra	DES	P17661	JPH3	Homo sapiens	Q8WXH2	Y2H Array	32814053
Intra	DES	P17661	JPH3	Homo sapiens	Q8WXH2	Validated Y2H	32814053
Intra	DES	P17661	JPH3	Homo sapiens	Q8WXH2	Y2H Pooling	32814053
Intra	DES	P17661	VIM	Homo sapiens	P08670	BFG-2H	27107012
Intra	DES	P17661	PRPH	Homo sapiens	P41219	Anti Tag CoIP	33961781
Intra	DES	P17661	VIM	Homo sapiens	P08670	Y2H Array	32296183
Intra	DES	P17661	GFAP	Homo sapiens	P14136	Validated Y2H	32814053
Intra	DES	P17661	NEFL	Homo sapiens	P07196	SLC	27107012
Intra	DES	P17661	VIM	Homo sapiens	P08670	Anti Tag CoIP	33961781
Intra	DES	P17661	NEFL	Homo sapiens	P07196	Y2H Array	32296183
Intra	DES	P17661	PRPH	Homo sapiens	P41219	Y2H Pooling	32814053
Intra	DES	P17661	VIM	Homo sapiens	P08670	Validated Y2H	27107012
Intra	DES	P17661	GFAP	Homo sapiens	P14136	Y2H Array	32814053
Intra	DES	P17661	PRPH	Homo sapiens	P41219	Validated Y2H	32296183
Intra	DES	P17661	GFAP	Homo sapiens	P14136	Y2H Pooling	32814053
Intra	DES	P17661	VIM	Homo sapiens	P08670	Y2H Prey Pooling	32296183
Intra	DES	P17661	PRPH	Homo sapiens	P41219	Validated Y2H	32814053
Intra	DES	P17661	NEFL	Homo sapiens	P07196	Anti Tag CoIP	33961781
Intra	DES	P17661	NEFL	Homo sapiens	P07196	Y2H Prey Pooling	32296183
Intra	DES	P17661	PRPH	Homo sapiens	P41219	Y2H Array	32814053
Intra	DES	P17661	TFIP11	Homo sapiens	Q9UBB9	Validated Y2H	32296183
Intra	DES	P17661	TFIP11	Homo sapiens	Q9UBB9	Y2H Prey Pooling	32296183
Intra	DES	P17661	TFIP11	Homo sapiens	Q9UBB9	Y2H Array	32296183
Intra	DES	P17661	DUX1	Homo sapiens	O43812	Pull Down	26816005
Intra	DES	P17661	DUX4	Homo sapiens	Q9UBX2	Pull Down	26816005
Intra	DES	P17661	NEK6	Homo sapiens	Q9HC98-4	Validated Y2H	32296183
Intra	DES	P17661	KRT13	Homo sapiens	P13646	Y2H Array	32296183
Intra	DES	P17661	KRT13	Homo sapiens	P13646	Y2H Prey Pooling	32296183
Intra	DES	P17661	ZMYM5	Homo sapiens	Q9UJ78-2	Y2H Array	32296183
Intra	DES	P17661	ZMYM5	Homo sapiens	Q9UJ78-2	Validated Y2H	32296183
Intra	DES	P17661	ZMYM5	Homo sapiens	Q9UJ78-2	Y2H Prey Pooling	32296183
Intra	DES	P17661	LBX1	Homo sapiens	P52954	Validated Y2H	32296183
Intra	DES	P17661	LBX1	Homo sapiens	P52954	Y2H Prey Pooling	32296183
Intra	DES	P17661	LBX1	Homo sapiens	P52954	Y2H Array	32296183
Intra	DES	P17661	EHHADH	Homo sapiens	Q08426	Validated Y2H	25416956
Intra	DES	P17661	EHHADH	Homo sapiens	Q08426	Y2H Prey Pooling	25416956
Intra	DES	P17661	EHHADH	Homo sapiens	Q08426	Validated Y2H	32296183
Intra	DES	P17661	EHHADH	Homo sapiens	Q08426	Y2H Array	25416956
Intra	DES	P17661	RNF4	Homo sapiens	P78317	Y2H Prey Pooling	32296183
Intra	DES	P17661	RNF4	Homo sapiens	P78317	Validated Y2H	32296183
Intra	DES	P17661	RNF4	Homo sapiens	P78317	Y2H Array	32296183
Intra	DES	P17661	PPP1R18	Homo sapiens	Q6NYC8	Y2H Prey Pooling	25416956
Intra	DES	P17661	PPP1R18	Homo sapiens	Q6NYC8	Validated Y2H	32296183
Intra	DES	P17661	PPP1R18	Homo sapiens	Q6NYC8	Y2H Array	25416956
Intra	DES	P17661	LONRF3	Homo sapiens	Q496Y0	Validated Y2H	32296183
Intra	DES	P17661	LMO4	Homo sapiens	P61968	Validated Y2H	32296183
Intra	DES	P17661	MTM1	Homo sapiens	Q13496	Y2H	21135508
Intra	DES	P17661	MTM1	Homo sapiens	Q13496	Cosedimentation	21135508
Intra	DES	P17661	MTM1	Homo sapiens	Q13496	Filter Binding	21135508
Intra	DES	P17661	MTM1	Homo sapiens	Q13496	Confocal	21135508
Intra	DES	P17661	MTM1	Homo sapiens	Q13496	Pull Down	21135508
Intra	DES	P17661	MTM1	Homo sapiens	Q13496	Anti Tag CoIP	21135508
Intra	DES	P17661	MTM1	Homo sapiens	Q13496	Far-WB	21135508
Intra	DES	P17661	KRT75	Homo sapiens	O95678	Y2H Prey Pooling	32296183
Intra	DES	P17661	KRT75	Homo sapiens	O95678	Y2H Array	32296183
Intra	DES	P17661	POLR2G	Homo sapiens	P62487	Y2H Prey Pooling	32296183
Intra	DES	P17661	POLR2G	Homo sapiens	P62487	Y2H Array	32296183
Intra	DES	P17661	POLR2G	Homo sapiens	P62487	Validated Y2H	32296183
Intra	DES	P17661	PIAS2	Homo sapiens	O75928-2	Y2H Prey Pooling	32296183
Intra	DES	P17661	PIAS2	Homo sapiens	O75928-2	Y2H Array	32296183
Intra	DES	P17661	DDX6	Homo sapiens	P26196	Validated Y2H	32296183
Intra	DES	P17661	BAG5	Homo sapiens	Q9UL15	Validated Y2H	32296183
Intra	DES	P17661	HTT	Homo sapiens	P42858	Validated Y2H	32814053
Intra	DES	P17661	HTT	Homo sapiens	P42858	Y2H Array	32814053
Intra	DES	P17661	HTT	Homo sapiens	P42858	Y2H Pooling	32814053
Intra	DES	P17661	CWF19L2	Homo sapiens	Q2TBE0	Validated Y2H	32296183
Intra	DES	P17661	GOLGA6L9	Homo sapiens	A6NEM1	Y2H Prey Pooling	32296183
Intra	DES	P17661	GOLGA6L9	Homo sapiens	A6NEM1	Y2H Array	32296183
Intra	DES	P17661	CT55	Homo sapiens	Q8WUE5	Y2H Array	32296183
Intra	DES	P17661	CT55	Homo sapiens	Q8WUE5	Validated Y2H	32296183
Intra	DES	P17661	CT55	Homo sapiens	Q8WUE5	Y2H Prey Pooling	32296183
Intra	DES	P17661	TCEA2	Homo sapiens	Q15560	Validated Y2H	32296183
Intra	DES	P17661	LENG1	Homo sapiens	Q96BZ8	Validated Y2H	32296183
Intra	DES	P17661	KRT15	Homo sapiens	P19012	Validated Y2H	32296183
Intra	DES	P17661	KRT15	Homo sapiens	P19012	Y2H Prey Pooling	32296183
Intra	DES	P17661	KRT15	Homo sapiens	P19012	Y2H Array	32296183
Intra	DES	P17661	KRT20	Homo sapiens	P35900	Validated Y2H	32296183
Intra	DES	P17661	MLH1	Homo sapiens	P40692	Anti Tag CoIP	20706999
Intra	DES	P17661	MLH1	Homo sapiens	P40692	Confocal	20706999
Intra	DES	P17661	MLH1	Homo sapiens	P40692	Y2H	20706999
Intra	DES	P17661	MLH1	Homo sapiens	P40692	Anti Bait CoIP	20706999
Intra	DES	P17661	C1orf216	Homo sapiens	Q8TAB5	Validated Y2H	32296183
Intra	DES	P17661	M1AP	Homo sapiens	Q8TC57	Validated Y2H	32296183

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant DES Proteins

Cat. No.	Product Name	Accession	Purity
HY-P70006	Desmin/DES Protein, Human (His)	P17661 (V261-L470)	≥ 90%, as determined by reducing SDS-PAGE.

DES Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P80103	Desmin Antibody (YA477)	WB, ICC/IF, IHC-P, FC	Human, Mouse, Rat
HY-P84139	Desmin Antibody (YA3836)	WB, IHC-P, FC, ELISA	Human, Mouse, Rat, Rabbit, Monkey
HY-P84139A	Desmin Antibody (YA3836)(PBS only)	WB, IHC-P, FC, ELISA	Human, Mouse, Rat, Rabbit, Monkey
HY-P85911	Desmin Antibody (YA5603)	IHC-P, WB, ICC/IF, ELISA	Human, Mouse, Rat
HY-P86054	Desmin Antibody (YA5746)	IHC-P, ELISA	Human, Mouse, Rat
HY-P86114	Desmin Antibody (YA5806)	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat

Related Diseases

Diseases	Alias
Myopathy, Myofibrillar, 1	Desmin-Related Myofibrillar Myopathy Desmin-Related Myopathy MFM1 Myopathy, Myofibrillar, Desmin-Related Drm Myofibrillar Myopathy With Arrhythmogenic Right Ventricular Cardiomyopathy Desmin-Related Myopathy With Arrhythmogenic Right Ventricular Cardiomyopathy Myofibrillar Myopathy 1 Desminopathy Muscular Dystrophy, Limb-Girdle, Type 2r Arrhythmogenic Right Ventricular Dysplasia, Familial, 7 Desminopathy, Primary Arrhythmogenic Right Ventricular Dysplasia, Familial, 7, Formerly Arvd7, Formerly Arrhythmogenic Right Ventricular Cardiomyopathy 7, Formerly Arvc7, Formerly Inclusion Body Myopathy 1, Autosomal Dominant, Formerly Ibm1, Formerly Cardiomyopathy, Dilated, 1f And Limb-Girdle Muscular Dystrophy Type 1d, Formerly Cmd1f And Lgmd1d, Formerly Cardiomyopathy, Dilated, With Conduction Defect And Muscular Dystrophy Cdcd3, Formerly Muscular Dystrophy, Limb-Girdle, Type 2r, Formerly Lgmd2r, Formerly Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2r Arrhythmogenic Right Ventricular Cardiomyopathy 7 Arvc7 Arvd7 Autosomal Dominant Inclusion Body Myopathy 1 Cdcd3 Cmd1f And Lgmd1d Desminopathy Primary Dilated Cardiomyopathy 1f And Limb-Girdle Muscular Dystrophy Type 1d Dilated Cardiomyopathy With Conduction Defect And Muscular Dystrophy Familial Arrhythmogenic Right Ventricular Dysplasia 7 Lgmd2r Limb-Girdle Muscular Dystrophy 2r Mfm Desmin-Related Myopathy Myofibrillar Desmin-Related Dystrophy, Muscular, Limb-Girdle, Type 2r
Scapuloperoneal Syndrome, Neurogenic, Kaeser Type	KAESER SYNDROME Stark-Kaeser Syndrome Neurogenic Scapuloperoneal Syndrome Kaeser Type Neurogenic Scapuloperoneal Syndrome, Kaeser Type Scapuloperoneal Syndrome, Neurogenic Type, Of Kaeser SCPNK Scapuloperoneal Syndrome Type Kaeser
Cardiomyopathy, Dilated, 1i	CMD1I Dilated Cardiomyopathy 1i Cardiomyopathy, Dilated 1i Cardiomyopathy, Dilated, Type 1i
Myofibrillar Myopathy	Desmin Related Myopathy Myotilinopathy Myopathy, Myofibrillar Alpha Beta Crystallinopathy Desmin Storage Myopathy Desminopathy Filaminopathy Protein Surplus Myopathy Zaspopathy Myofibrillar Myopathies Myopathy, Myofibrillar, Desmin-Related Myopathy, Desmin Storage Mfm - [Myofibrillar Myopathy]
Dilated Cardiomyopathy	Familial Dilated Cardiomyopathy Primary Dilated Cardiomyopathy Idiopathic Dilated Cardiomyopathy Congestive Cardiomyopathy Idiopathic Dilation Cardiomyopathy Primary Familial Dilated Cardiomyopathy Cardiomyopathy, Dilated DCM Cardiomyopathy, Familial Dilated Dilated Cardiomyopathy, Familial Hypokinetic Dilated Cardiomyopathy, Familial Familial Idiopathic Cardiomyopathy Fdc Cardiomyopathy, Familial Idiopathic Idiopathic Cardiomegaly Dilated Congestive Cardiomyopathy Chronic Dilated Cardiomyopathy Ccm - [Congestive Cardiomyopathy] Cocm - [Congestive Cardiomyopathy] Dcm - [Dilated Cardiomyopathy] Dilated-Hypokinetic Cardiomyopathy Congestive Idiopathic Cardiomyopathy Primary Idiopathic Dilated Cardiomyopathy
Cardiomyopathy, Dilated, 1e	Left Ventricular Noncompaction 9 Left Ventricular Noncompaction 5 Dilated Cardiomyopathy 1e Dilated Cardiomyopathy 1s CMD1E Cdcd2 Cardiomyopathy, Dilated, 1y CMD1Y Cardiomyopathy, Dilated, 1s CMD1S Dilated Cardiomyopathy 1y Dilated Cardiomyopathy With Conduction Defect 2 Dilated Cardiomyopathy With Conduction Disorder And Arrhythmia Cardiomyopathy, Dilated, With Conduction Disorder And Arrhythmia Cardiomyopathy, Dilated, With Conduction Defect 2 Cardiomyopathy Dilated With Conduction Defect Type 2 Cardiomyopathy, Dilated 1e Cardiomyopathy, Dilated 1s Cardiomyopathy, Dilated 1y Left Ventricular Non-Compaction 5 LVNC5 Left Ventricular Non-Compaction 9 LVNC9 Cardiomyopathy, Dilated, Type 1e Cardiomyopathy, Dilated, Type 1s Cardiomyopathy, Dilated, Type 1y
Arrhythmogenic Right Ventricular Cardiomyopathy	Arrhythmogenic Right Ventricular Dysplasia Arvc Arvd Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Arvc Cardiomyopathy Arrhythmogenic Right Ventricular Cardiomyopathy-Dysplasia Arvd/C Right Ventricular Dysplasia, Arrhythmogenic Ventricular Dysplasia, Right, Arrhythmogenic Cardiomyopathy, Ventricular, Right, Arrhythmogenic Dysplasia, Arrhythmogenic Right Ventricular
Familial Isolated Dilated Cardiomyopathy	Familial Or Idiopathic Dilated Cardiomyopathy
Progressive Familial Heart Block	Hereditary Bundle Branch Defect Hereditary Bundle Branch System Defect Familial Lenegre Disease Familial Lev Disease Familial Lev-Lenegre Disease Familial Pccd Familial Progressive Heart Block Pfhb Bundle Branch Block Hbbd Lenegre Lev Disease Lev Syndrome Lev'S Disease Lev-Lenègre Disease Pccd Progressive Cardiac Conduction Defect Bundle-Branch Block
Progressive Familial Heart Block, Type Ia	PFHB1A Bundle Branch Block Heart Block, Nonprogressive Lenegre-Lev Disease Hereditary Bundle Branch System Defect Progressive Familial Heart Block Type Ia Pfhbia Pccd Hbbd Progressive Familial Heart Block, Type 1a Heart Block, Progressive Familial, Type I Pfhbi Cardiac Conduction Defect, Progressive Heart Block, Progressive, Type Ia Progressive Familial Heart Block Type 1a Familial Progressive Cardiac Conduction Defect Heart Block Progressive Familial Type 1 Familial Lenègre Disease Familial Lev Disease Familial Lev-Lenègre Disease Familial Pccd Familial Progressive Heart Block Hereditary Bundle Branch Defect Progressive Familial Heart Block Progressive Familial Heart Block 1a Cardiac Conduction Defect Progressive Cardiac Conduction Defect Progressive Familial Heart Block Type I Heart Block, Progressive, Familial, Type 1a Bundle-Branch Block Conduction Disorder Of The Heart
Lymphangioleiomyomatosis	Lymphangiomyomatosis LAM Lung Lymphangioleiomyomatosis Pulmonary Lymphangioleiomyomatosis Lymphangioleiomyomatosis, Somatic Lymphangio-Myomatosis
Neuromuscular Disease	Neuromuscular Diseases Neuromuscular Disorders Neuromuscular Disorder
Mesenchymal Chondrosarcoma	Chondrosarcoma, Mesenchymal Chondrosarcoma Mesenchymal
Epithelioid Leiomyosarcoma	Leiomyosarcoma Epithelioid Leiomyosarcoma, Epithelioid
Adenosarcoma	Mullerian Adenosarcoma
Cardioneuromyopathy With Hyaline Masses And Nemaline Rods
Restrictive Cardiomyopathy	Familial Restrictive Cardiomyopathy Cardiomyopathy, Restrictive Cardiomyopathy, Constrictive Primary Restrictive Cardiomyopathy Rcm Cardiomyopathy Restrictive
Dedifferentiated Liposarcoma	Ddls Liposarcoma Dedifferentiated Liposarcoma, Dedifferentiated
Fibromatosis
Glomus Tumor	Glomus Neoplasm Glomus Tumour
Myopathy	Muscular Diseases Myopathies
Alveolar Soft Part Sarcoma	ASPS Alveolar Soft-Part Sarcoma Sarcoma, Alveolar Soft Part Alveolar Soft Tissue Sarcoma Sarcoma Alveolar Soft Part Adult Alveolar Soft-Part Sarcoma Childhood Alveolar Soft-Part Sarcoma
Leiomyosarcoma	Leiomyosarcomas
Fibroma
Carcinosarcoma	Mixed Tumor, Mullerian Malignant Mixed Mesodermal Tumor Malignant Mixed Mullerian Tumor Mmmt Mixed Tumor, Mesodermal Mesodermal Mixed Tumor Mixed Mesodermal Tumor Mullerian Mixed Tumor Mixed Mullerian Tumor Malignant Mixed Müllerian Tumor Mixed Müllerian Tumor Mixed Tumor Mullerian Mixed Tumor, Not Otherwise Specified
Fibrous Histiocytoma	Benign Fibrous Histiocytoma Histiocytoma, Benign Fibrous Fibroxanthoma Histiocytoma Fibrous
Embryonal Rhabdomyosarcoma	Rhabdomyosarcoma, Embryonal Rhabdomyosarcoma Embryonal Botryoid Rhabdomyosarcoma Erms Spindle Cell Rhabdomyosarcomas
Granular Cell Tumor	Abrikosov'S Tumor Neoplasm Of Granular Cell Abrikosoff'S Granulous Cell Tumor Abrikosoff'S Tumor Giant Granulocellular Abrikosov'S Tumor Malignant Variant Of Abrikosov'S Tumor Carcinoma, Granular Cell
Myopathy, Spheroid Body	Spheroid Body Myopathy Autosomal Dominant Spheroid Body Myopathy SBM
Medullary Colon Carcinoma
Angiomyolipoma	Angiomyolipoma Of Kidney
Endometrial Stromal Sarcoma	Ess Endometrial Stromal Sarcoma, High Grade Undifferentiated Endometrial Sarcoma Stromal Sarcoma Of The Corpus Uteri Sarcoma Endometrial Stromal Sarcoma, Endometrial Stromal Undifferentiated Stromal Sarcoma
Dermatofibrosarcoma Protuberans	DFSP Dermatofibrosarcoma Giant Cell Fibroblastoma Metastatic Dermatofibrosarcoma Protuberans Familial Dermatofibrosarcoma Protuberans Darier-Ferrand Tumor Darier-Hoffmann Tumor
Desmoplastic Small Round Cell Tumor	Dsrct Desmoplastic Small Round-Cell Tumor Desmoplastic Small Round-Cell Neoplasm
Miyoshi Muscular Dystrophy	Distal Myopathy Distal Muscular Dystrophy Miyoshi Myopathy Distal Myopathies Dystrophy, Muscular, Miyoshi Myopathy, Distal Distal Muscular Dystrophies
Leiomyoma	Leiomyomatous Neoplasm Leiomyomatous Tumor Leiomyomas Fibroid Tumor Uterine Fibroids
Malignant Fibrous Histiocytoma	Undifferentiated Pleomorphic Sarcoma Ups Histiocytoma, Malignant Fibrous Fibroxanthosarcoma Mfh Malignant Fibrohistiocytic Tumors Histiocytoma, Fibrous, Malignant
Infantile Myofibromatosis	Lipofibromatosis Myofibromatosis
Cardiomyopathy, Familial Hypertrophic, 1	Asymmetric Septal Hypertrophy Familial Hypertrophic Cardiomyopathy Hypertrophic Cardiomyopathy 1 CMH1 Hypertrophic Cardiomyopathy 19 CMH Ventricular Hypertrophy, Hereditary Ash Hypertrophic Subaortic Stenosis, Idiopathic Cardiomyopathy, Familial Hypertrophic Cardiomyopathy, Hypertrophic, 1, Digenic Cardiomyopathy, Familial Hypertrophic 1 Hcm Hereditary Ventricular Hypertrophy Idiopathic Hypertrophic Subaortic Stenosis Hypertrophic Cardiomyopathy Cardiomyopathy, Hypertrophic, Familial Cardiomyopathy, Hypertrophic, 1 Familial Asymmetric Septal Hypertrophy Heritable Hypertrophic Cardiomyopathy Fhc Cardiomyopathy, Hypertrophic, Familial, Type 1
Liposarcoma	Lipomatous Cancer
Gastrointestinal Stromal Tumor	GIST Gastrointestinal Stromal Tumors Gastrointestinal Stromal Sarcoma Gastrointestinal Stromal Tumor, Familial Gant Gastrointestinal Stromal Tumour Stromal Tumor Of Gastrointestinal Tract Stromal Tumour Of Gastrointestinal Tract Gastrointestinal Stromal Neoplasm Paraganglioma And Gastric Stromal Sarcoma Plexosarcoma
Muscle Cancer	Myosarcoma Malignant Neoplasm Of Muscle Malignant Tumor Of Muscle Malignant Tumor Of The Muscle Muscle Neoplasms Myomatous Neoplasm
Angiolipoma
Uterus Leiomyosarcoma	Leiomyosarcoma Of Uterus Leiomyosarcoma Of Corpus Uteri Leiomyosarcoma Of The Corpus Uteri Uterine Leiomyosarcoma
Uterine Sarcoma	Sarcoma Of The Uterus Uterine Corpus Sarcoma
Pseudosarcomatous Fibromatosis	Nodular Fasciitis Pseudosarcomatous Fasciitis Fasciitis - Nodular Fasciitis Nodular
Smooth Muscle Tumor
Pleomorphic Adenoma	Mixed Tumor Of The Salivary Gland Adenoma Pleomorphic Adenoma, Pleomorphic Mixed Salivary Gland Tumor Mixed Tumor, Not Otherwise Specified
Spindle Cell Sarcoma	Sarcoma Sarcoma Spindle Cell Sarcoma, Spindle Cell Sarcoma - Category
Atrioventricular Block	Av Block
Hemangiopericytoma, Malignant	Hemangiopericytoma Haemangiopericytic Meningioma Malignant Hemangiopericytoma Solitary Fibrous Tumor
Centronuclear Myopathy	Myopathy, Centronuclear Myotubular Myopathy Cnm Myopathy, Myotubular Congenital Structural Myopathy
Rhabdomyosarcoma
Muscular Dystrophy, Limb-Girdle, Autosomal Recessive 2	Lgmd2b Muscular Dystrophy, Limb-Girdle, Type 2b Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2e Beta-Sarcoglycanopathy Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2y Muscular Dystrophy, Limb-Girdle, Type 3 Lgmd3 Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2s LGMDR2 Muscular Dystrophy, Limb-Girdle, Type 2s Limb-Girdle Muscular Dystrophy Type 2b Lgmd2e Limb-Girdle Muscular Dystrophy Due To Beta-Sarcoglycan Deficiency Muscular Dystrophy, Limb-Girdle, Type 2e Lgmd2s Autosomal Recessive Muscular Dystrophy Due To Lap1b Deficiency Autosomal Recessive Muscular Dystrophy Due To Torsin-1a-Interacting Protein 1 Deficiency Lgmd2y Muscular Dystrophy With Progressive Weakness, Distal Contractures And Rigid Spine Muscular Dystrophy, Limb-Girdle, Type 2y Dysferlin-Related Limb-Girdle Muscular Dystrophy R2 Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2b Dysferlin-Related Lgmd R2 Lgmd Due To Dysferlin Deficiency Lgmd Type 2b Limb-Girdle Muscular Dystrophy Due To Dysferlin Deficiency Limb-Girdle Muscular Dystrophy 2b Limb-Girdle Muscular Dystrophy, Type 2b Dystrophy, Muscular, Limb-Girdle, Autosomal Recessive, Type 2 Dystrophy, Muscular, Limb-Girdle, Type 2b Limb-Girdle Muscular Dystrophy, Type 2e
Batten-Turner Congenital Myopathy	Congenital Myopathy Batten Turner Congenital Myopathy Myopathy Congenital Myopathy, Congenital Myotonia Congenita Benign Congenital Myopathy
Cutaneous Fibrous Histiocytoma	Dermatofibroma Fibrohistiocytic Tumor Benign Cutaneous Fibrous Histiocytoma Fibrous Histiocytoma Of Skin Fibrous Xanthoma Of Skin Pleomorphic Fibroma Sclerosing Angioma Sclerosing Angioma Of Skin Fibrous Histiocytoma
Chordoma	CHDM Notochordoma Notochordal Sarcoma Chordoma, Susceptibility To Chordocarcinoma Chordoepithelioma
Rhabdoid Cancer	Rhabdoid Tumor Malignant Rhabdoid Tumor Malignant Rhabdoid Tumour Rhabdoid Sarcoma Rhabdoid Tumor Predisposition Syndrome 1 Rhabdoid Tumor Predisposition Syndrome 2 Atypical Teratoid Rhabdoid Tumor Brain Tumor, Posterior Fossa, Of Infancy, Familial Atypical Teratoid/Rhabdoid Tumor
Muscular Dystrophy-Dystroglycanopathy , Type C, 7	Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2u Lgmd2u MDDGC7 Muscular Dystrophy, Limb-Girdle, Autosomal Recessive 20 Lgmdr20 Muscular Dystrophy, Limb-Girdle, Type 2u Autosomal Recessive Limb-Girdle Muscular Dystrophy Due To Ispd Deficiency Muscular Dystrophy Limb-Girdle Type 2u Muscular Dystrophy-Dystroglycanopathy Type C7 Ispd-Related Limb-Girdle Muscular Dystrophy R20 Ispd-Related Lgmd R20 Lgmd Type 2u Limb-Girdle Muscular Dystrophy Type 2u Muscular Dystrophy-Dystroglycanopathy Limb-Girdle C7 Dystrophy, Muscular, Dystroglycanopathy, Type C7
Muscular Dystrophy-Dystroglycanopathy , Type C, 14	Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2t Lgmd2t MDDGC14 Muscular Dystrophy, Limb-Girdle, Autosomal Recessive 19 Lgmdr19 Muscular Dystrophy Limb-Girdle Type 2t Muscular Dystrophy-Dystroglycanopathy Limb-Girdle Gmppb-Related Muscular Dystrophy, Limb-Girdle, Type 2t Muscular Dystrophy-Dystroglycanopathy, Limb-Girdle, Gmppb-Related Muscular Dystrophy-Dystroglycanopathy Type C14 Gmppb-Related Limb-Girdle Muscular Dystrophy R19 Gmppb-Related Lgmd R19 Lgmd Type 2t Limb-Girdle Muscular Dystrophy Type 2t Muscular Dystrophy-Dystroglycanopathy Limb-Girdle C14 Dystrophy, Muscular, Limb-Girdle, Type 2t
Rhabdomyosarcoma 2	Alveolar Rhabdomyosarcoma Rhabdomyosarcoma, Alveolar Rhabdomyosarcoma Alveolar RMS2 Rmsa Rhabdomyosarcoma 2, Alveolar Alveolar Childhood Rhabdomyosarcoma Arms Rhabdomyosarcoma, Type 2
Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2w	Lgmd2w Muscular Dystrophy, Limb-Girdle, Type 2w
Fibrosarcoma	Neoplasms, Fibrous Tissue Fibrocytic Tumor Fibrosarcoma Of Soft Tissue Fibrous Tissue Neoplasm
Pulmonary Blastoma	Blastoma Of Lung Pneumoblastoma
Syringoma	Syringomas
Muscular Dystrophy-Dystroglycanopathy , Type C, 9	Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2p Lgmd2p MDDGC9 Muscular Dystrophy, Limb-Girdle, Autosomal Recessive 16 Lgmdr16 Muscular Dystrophy-Dystroglycanopathy Limb-Girdle Dag1-Related Muscular Dystrophy, Limb-Girdle, Type 2p Muscular Dystrophy-Dystroglycanopathy, Limb-Girdle, Dag1-Related Muscular Dystrophy-Dystroglycanopathy Type C9 Alpha-Dystroglycan-Related Limb-Girdle Muscular Dystrophy R16 Alpha-Dystroglycan-Related Lgmd R16 Lgmd Type 2p Limb-Girdle Muscular Dystrophy Type 2p Muscular Dystrophy-Dystroglycanopathy Limb-Girdle C9 Muscular Dystrophy Limb-Girdle Type 2p Dystrophy, Muscular, Limb-Girdle, Type 2p
Central Core Disease Of Muscle	Central Core Disease Central Core Myopathy CCD Cco Neuromuscular Disease, Congenital, With Uniform Type 1 Fiber Myopathy, Central Core Shy-Magee Syndrome Muscle Core Disease Muscular Central Core Disease Myopathy, Central Fibrillar Shy'S Disease Moderate Multiminicore Disease With Hand Involvement
Nephroma	Benign Nephroma
Adenomatoid Tumor	Adenomatoid Tumour Benign Localised Epithelial Mesothelioma Benign Localized Epithelial Mesothelioma
Neuroleptic Malignant Syndrome
Muscular Dystrophy	Muscular Dystrophies Congenital Md Congenital Muscular Dystrophy Cmd Mdc Dystrophy, Muscular Gower'S Muscular Dystrophy Progressive Musclular Dystrophy Pseudohypertrophic Atrophy Pseudohypertrophic Muscle Paralysis Pseudohypertrophic Muscular Atrophy Pseudohypertrophic Muscular Dystrophy Pseudohypertrophic Paralysis Pseudomuscular Hypertrophy
Sertoli-Leydig Cell Tumor	Sertoli-Leydig Cell Tumors Androblastoma Of Ovary Arrhenoblastoma Arrhenoblastoma Of Ovary Sertoli-Leydig Cell Tumor Of The Ovary Sertoli-Leydig Cell Tumor Of Intermediate Differentiation Sertoli-Leydig Cell Tumor Of Ovary
Perineurioma	Soft Tissue Perineurioma
Myoepithelioma	Benign Myoepithelioma Myoepithelial Adenoma Myoepithelial Neoplasm Malignant Myoepithelioma
Limb-Girdle Muscular Dystrophy	Lgmd Limb Girdle Muscular Dystrophy Muscular Dystrophies, Limb-Girdle Erb'S Muscular Dystrophy Leyden-Mbius Muscular Dystrophy Limb-Girdle Syndrome Myopathic Limb-Girdle Syndrome Limb Girdle Muscular Dystrophy Limb-Girdle Dystrophy, Muscular, Limb-Girdle Lgmd - [Limb-Girdle Muscular Dystrophy] Limb Girdle Muscle Dystrophy Limb-Girdle Myopathy
Immunodeficiency 48	Combined Immunodeficiency Due To Zap70 Deficiency IMD48 Selective T-Cell Defect Stcd Zeta-Associated-Protein 70 Deficiency Severe Combined Immunodeficiency, Atypical Immunodeficiency, Type 48 Zap70 Deficiency
Leiomyomatosis
Echinostomiasis	Infection By Echinochasmus
Muscular Dystrophy, Limb-Girdle, Autosomal Dominant 1	Muscular Dystrophy, Limb-Girdle, Type 1e Lgmd1d Autosomal Dominant Limb-Girdle Muscular Dystrophy Type 1d LGMDD1 Lgmd1e Autosomal Dominant Limb-Girdle Muscular Dystrophy Type 1 Limb-Girdle Muscular Dystrophy Type 1d Muscular Dystrophy, Limb-Girdle, Type 1d Muscular Dystrophy, Limb-Girdle, Type 1d, Formerly Lgmd1d, Formerly Autosomal Dominant Limb-Girdle Muscular Dystrophy Type 1e Muscular Dystrophy Limb-Girdle Type 1d Muscular Dystrophy Limb-Girdle Type 1e Dnajb6-Related Limb-Girdle Muscular Dystrophy D1 Dnajb6-Related Lgmd D1 Lgmd Type 1d Limb-Girdle Muscular Dystrophy 1e Limb-Girdle Muscular Dystrophy-1d, Autosomal Dominant Dystrophy, Muscular, Limb-Girdle, Autosomal Dominant, Type 1 Dystrophy, Muscular, Limb-Girdle, Type 1e
Benign Giant Cell Tumor	Giant Cell Tumors
Lipomatosis, Multiple	Lipoma Familial Multiple Lipomatosis Lipomatosis, Familial Multiple Benign Lipomatous Tumor Lipomatous Neoplasm Multiple Lipomatosis Fml Lipo Benign Tumor Of Adipose Tissue Lipomatous Tumor Tumor Of Adipose Tissue Neoplasms, Adipose Tissue Lipomas
Desmoid Tumor	Aggressive Fibromatosis Desmoid Type Fibromatosis Familial Infiltrative Fibromatosis Desmoid Disorder, Hereditary Fif Fibromatosis, Familial Infiltrative Deep Fibromatosis Desmoid Fibromatosis Hereditary Desmoid Disease Musculoaponeurotic Fibromatosis Desmoid-Type Fibromatosis Fibromatosis, Aggressive Desmoid Disease, Hereditary Musculo-Aponeurotic Fibromatosis
Muscular Dystrophy, Limb-Girdle, Autosomal Dominant 3	Lgmd1g Autosomal Dominant Limb-Girdle Muscular Dystrophy Type 1g LGMDD3 Muscular Dystrophy, Limb-Girdle, Type 1g Autosomal Dominant Limb-Girdle Muscular Dystrophy Type 3 Limb-Girdle Muscular Dystrophy, Type 1g Muscular Dystrophy Limb-Girdle Type 1g Hnrnpdl-Related Limb-Girdle Muscular Dystrophy D3 Hnrnpdl-Related Lgmd D3 Lgmd Type 1g Limb-Girdle Muscular Dystrophy Type 1g Limb-Girdle Muscular Dystrophy 1g Dystrophy, Muscular, Limb-Girdle, Type 1g
Neurilemmoma	Schwannoma Benign Schwannoma Neurilemoma Peripheral Fibroblastoma Psammomatous Schwannoma Neurolemmoma Schwannomas
Castleman Disease	Angiofollicular Ganglionic Hyperplasia Angiofollicular Lymph Hyperplasia Giant Lymph Node Hyperplasia Castleman'S Disease Angiofollicular Lymph Node Hyperplasia Lymphoid Hamartoma Benign Giant Lymphoma Angiolymphoid Hyperplasia
Fasciitis
Atrial Standstill 1	ATRST1 Atrial Cardiomyopathy With Heart Block Cardiomyopathy, Familial, With Conduction Disturbance Atrial Standstill, Digenic Familial Cardiomyopathy With Conduction Disturbance Standstill, Atrial, Type 1 Heart Block Cardiomyopathies Idiopathic Cardiomyopathy Idiopathic Cardiopathy Primary Myocardial Disease Primary Cardiomyopathy Myocardiopathy Myocardosis Primary Idiopathic Myocardial Disease
Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2g	Lgmd2g Limb-Girdle Muscular Dystrophy Due To Telethonin Deficiency Muscular Dystrophy, Limb-Girdle, Type 2g
Autosomal Recessive Limb-Girdle Muscular Dystrophy Type 2j	Lgmd2j Muscular Dystrophy, Limb-Girdle, Type 2j
Coffin-Siris Syndrome 1	Coffin-Siris Syndrome Fifth Digit Syndrome Css CSS1 Mrd12 Mental Retardation, Autosomal Dominant 12 Hhid Dwarfism-Onychodysplasia Hypertrichosis, Hyperkeratosis, Mental Retardation, And Distinctive Facial Features Autosomal Dominant Mental Retardation 12 Short Stature-Onychodysplasia. Intellectual Disability With Absent Fifth Fingernail And Terminal Phalanx Mental Retardation With Hypoplastic Fifth Fingernails And Toenails Short Stature-Onychodysplasia Coffin-Siris Syndrome, Type 1 Mental Retardation, Autosomal Dominant, Type 12
Sarcoma, Synovial	Synovial Sarcoma Synovialosarcoma Synovial Cell Sarcoma Sarcoma Synovial
Pneumothorax	Pneumothorax Nos Air Leak Nos Pleural Air Leak Nos
Myasthenic Syndrome, Congenital, 6, Presynaptic	Familial Infantile Myasthenia CMS6 Cmsea Congenital Myasthenic Syndrome 6 Familial Infantile Myasthenia Gravis 2 Fimg2 Myasthenic Syndrome, Congenital, Associated With Episodic Apnea Myasthenic Syndrome, Presynaptic, Congenital, Associated With Episodic Apnea Congenital Myasthenic Syndrome Type Ia2, Formerly Cms1a2, Formerly Cms Ia2, Formerly Myasthenia, Familial Infantile, Formerly Fim, Formerly Myasthenia Gravis, Familial Infantile, 2, Formerly Fimg2, Formerly Cms Ia2 Cms1a2 Congenital Myasthenic Syndrome 6, Presynaptic Congenital Myasthenic Syndrome Type Ia2 Congenital Presynaptic Myasthenic Syndrome Associated With Episodic Apnea Fim Cms1a Cms-Ea Cms Ia Congenital Myasthenic Syndrome Pre-Synaptic Associated With Episodic Apnea Congenital Myasthenic Syndrome Type 1a Congenital Myasthenic Syndrome Type Ia Myasthenic Syndrome, Congenital, Type 6, Presynaptic
Lipodystrophy, Familial Partial, Type 6	FPLD6 Lipe-Related Familial Partial Lipodystrophy Familial Partial Lipodystrophy Type 6 Lipe-Related Fpld Lipodystrophy, Familial Partial, Associated With Lipe Mutations Familial Partial Lipodystrophy Associated With Lipe Mutations Lipodystrophy, Familial Partial, 6
Myopathy, Myofibrillar, 3	Myotilinopathy Myofibrillar Myopathy 3 MFM3 Autosomal Dominant Limb-Girdle Muscular Dystrophy Type 1a Lgmd1a Muscular Dystrophy, Limb-Girdle, Type 1a Myopathy, Myofibrillar, Myotilin-Related Muscular Dystrophy, Limb-Girdle, Type 1, Formerly Lgmd1, Formerly Muscular Dystrophy, Limb-Girdle, Type 1a, Formerly Lgmd1a, Formerly Qualitative Or Quantitative Defects Of Myotilin Limb-Girdle Muscular Dystrophy Due To Myotilin Deficiency Distal Myotilinopathy Lgmd1 Limb-Girdle Muscular Dystrophy 1a Mfm Myotilin-Related Muscular Dystrophy, Limb-Girdle, Type 1 Myopathy Myofibrillar Myotylin-Related Myopathy, Myofibrillar, Type 3
Medulloblastoma	MDB Cpnet Localized Primitive Neuroectodermal Tumor Classic Medulloblastoma Medulloblastoma Predisposition Syndrome Medulloblastoma, Somatic Brain Medulloblastoma Cns Pnet Infratentorial Primitive Neuroectodermal Tumor Neuroectodermal Tumors, Primitive Medulloblastomas Desmoplastic Medulloblastoma Medulloblastoma, With Extensive Nodularity Medulloblastoma Of Unspecified Site Medullomyoblastoma Of Unspecified Site
Achalasia	Cardiospasm Achalasia Of Cardia Esophageal Achalasia Hypertensive Lower Esophageal Sphincter Idiopathic Achalasia Achalasia Cardia Idiopathic Achalasia Of Esophagus Primary Achalasia Achalasia Of Esophagus Lack Of Reflex Relaxation Of Lower Oesophageal Sphincter Aperistalsis Of The Oesophagus Achalasia Of Oesophagus Oesophageal Achalasia Achalasia Nos Cardia Spasm Cardia Achalasia Oesophageal Cardiospasm Oesophagus Achalasia Reflex Cardiospasm
Hypertrophic Cardiomyopathy	Hypertrophic Obstructive Cardiomyopathy Cardiomyopathy, Hypertrophic Cardiomyopathy Hypertrophic Obstructive Cardiomyopathy, Hypertrophic, Familial Idiopathic Myocardial Hypertrophy Idiopathic Hypertrophic Cardiomyopathy Obstructive Idiopathic Hypertrophic Cardiomyopathy Obstructive Cardiomyopathy Idiopathic Hypertrophic Subaortic Stenosis Muscular Subaortic Stenosis Hypertrophic Obstructive Subaortic Stenosis
Ewing Sarcoma	Neuroepithelioma Ewing'S Tumor Primitive Neuroectodermal Tumor Ewings Sarcoma Ewing'S Sarcoma Peripheral Neuroepithelioma ES Ewings Sarcoma-Primitive Neuroectodermal Tumor Localized Peripheral Primitive Neuroectodermal Tumor Peripheral Primitive Neuroectodermal Tumor Ewing Tumor Sarcoma, Ewing'S Ewing Family Of Tumors Extraosseous Ewing Tumor Askin Tumor Ewing'S Family Localized Tumor Ewing'S Sarcoma/Peripheral Primitive Neuroectodermal Tumor Localized Ewing Sarcoma Localized Ewing'S Sarcoma Localized Ewing'S Sarcoma/Peripheral Primitive Neuroectodermal Tumor Localized Ewing'S Tumor Pnet Of Thoracopulmonary Region Tumor Of The Ewing Family Skeletal Ewing Sarcoma Osseous Ewing Sarcoma Ppnet Peripheral Pnet Extraskeletal Ewing Sarcoma Eoe Extraosseous Ewing Sarcoma Extraskeletal Ewing Tumor Esft Ewing Sarcoma Family Of Tumors Pne Pnet Pnet Of The Chest Wall Sarcoma, Ewing Neuroectodermal Tumors, Primitive, Peripheral Neuroectodermal Tumor, Primitive Disorder Of Eye Askin'S Tumor Extraosseous Ewings Sarcoma-Primitive Neuroepithelial Tumor Neuroepithelioma, Peripheral
Cardiomyopathy, Dilated, 1h	Dilated Cardiomyopathy 1h Dilated Cardiomyopathy With Conduction Defect CMD1H Cardiomyopathy, Dilated, With Conduction Defect
Muscular Dystrophy, Duchenne Type	Duchenne Muscular Dystrophy DMD Muscular Dystrophy, Duchenne Muscular Dystrophy, Pseudohypertrophic Progressive, Duchenne Type Severe Dystrophinopathy, Duchenne Type Muscular Dystrophy Duchenne Dystrophy, Muscular, Duchenne Type Benign Duchenne Muscular Dystrophy Duchenne Motor Neuron Disease Duchenne Type Dystrophy Duchenne-Griesinger Disease
Constipation

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Approval
Clinical Phase
Pre-clinical Phase

Approval

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-14598	Diethylstilbestrol		99.62%	Unkown
HY-P0048	(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH	Agonist	99.53%	Unkown

Clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P2088	TANDEM		/	Phase 4

Pre-clinical Phase

Bioactive Molecules (67)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P0298A	[Des-Arg9]-Bradykinin acetate	Agonist	99.87%	Unkown
HY-P1366	des-Gln14-Ghrelin		98.21%	Unkown
HY-N9542	Dimethyl Citric acid		97.0%	Unkown
HY-P1143A	[Des-His1,Glu9]-Glucagon amide TFA	Antagonist	98.36%	Unkown
HY-122402	Umirolimus		98.83%	Unkown
HY-P1526	ANP [Des18-22] 4-23 amide (rat)	Ligand	99.16%	Unkown
HY-103295A	Lys-[Des-Arg9]Bradykinin TFA	Agonist	99.31%	Unkown
HY-103291	Sar-[D-Phe8]-des-Arg9-Bradykinin	Agonist	99.96%	Unkown
HY-P4676	Lys-(Des-Arg9,Leu8)-Bradykinin	Antagonist	98.23%	Unkown
HY-W040270	Amino-PEG10-amine		97.0%	Unkown
HY-P2828	[Des-Pro2]-Bradykinin	Inhibitor	99.68%	Unkown
HY-122402S	Umirolimus-d5	Inhibitor	99.96%	Unkown
HY-130411	Amino-PEG11-amine		95.0%	Unkown
HY-P0298	[Des-Arg9]-Bradykinin	Agonist	/	Unkown
HY-P11363	(Des-Asp1,Ile8)-Angiotensin II		98.93%	Unkown
HY-P1143	[Des-His1,Glu9]-Glucagon amide	Antagonist	99.32%	Unkown
HY-P1490	Bradykinin (2-9)	Modulator	97.15%	Unkown
HY-P3209	Des-Arg9-[Leu8]-Bradykinin acetate	Inhibitor	98.36%	Unkown
HY-P4463	(Des-Pyr1)-LHRH		99.26%	Unkown
HY-P4683	(Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin	Antagonist	/	Unkown
HY-P4683A	(Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin acetate	Antagonist	99.81%	Unkown
HY-W017448	Mepiquat chloride		98.0%	Unkown
HY-N11758	5′-Des-O-methylharringtonine		99.80%	Unkown
HY-P5518A	[Des-Arg10]-HOE I40 TFA	Antagonist	99.84%	Unkown
HY-132684S	7-Benzyloxy-N-des[[2-(2-hydroxy)ethoxy]ethyl] Quetiapine-d8		/	Unkown
HY-132795S	Des(1-cyclohexanol) Venlafaxine-d6		/	Unkown
HY-141757S	Des-p-fluorobenzyl mosapride-d5		/	Unkown
HY-103295	Lys-[Des-Arg9]Bradykinin	Agonist	/	Unkown
HY-15899	Des(benzylpyridyl) Atazanavir	Inhibitor	/	Unkown
HY-163472	PR280	Inhibitor	98.69%	Unkown
HY-183723	GAA-4OH	Inhibitor	/	Unkown
HY-B2192A	Diastase, Aspergillus oryzae		/	Unkown
HY-CE00411	(S)-Des-Me-ampa-CoA		/	Unkown
HY-D1346	610CP		/	Unkown
HY-N16393	(-)-Mitorubrinol		/	Unkown
HY-N17355	Des-N-methylnoracronycine		/	Unkown
HY-P10498	[Des-Tyr1]-gamma-Endorphin		/	Unkown
HY-P11463	Des-threoninol-octreotide	Inhibitor	/	Unkown
HY-P1366A	des-Gln14-Ghrelin TFA		/	Unkown
HY-P2658	[Des-Tyr1]-Met-Enkephalin		/	Unkown
HY-P3006	Des-Leu10-angiotensin I		/	Unkown
HY-P3542	Des His1, Glu8 Exendin-4	Antagonist	/	Unkown
HY-P3583	(Des-Gly10,D-Arg6,Pro-NHEt9)-LHRH II (chicken)		/	Unkown
HY-P3608	[Des-His1,Glu9] Glucagon	Antagonist	/	Unkown
HY-P4397	(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin		/	Unkown
HY-P4413	(Des-Glu5)-ACTH (1-24) (human, bovine, rat)		/	Unkown
HY-P4414	(Des-Bromo)-Neuropeptide B (1-23) (human)	Agonist	/	Unkown
HY-P4432	(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon)	Activator	/	Unkown
HY-P4440	(Des-Gly10,Des-Ser4,D-Leu6,Pro-NHEt9)-LHRH		/	Unkown
HY-P4441	(Des-Gly10,D-His2,D-His(Bzl)6,Pro-NHEt9)-LHRH		/	Unkown
HY-P4442	(Des-Gly10,D-His2,D-Trp6,Pro-NHEt9)-LHRH		/	Unkown
HY-P4445	(Des-Gly10,D-Leu6,Orn8,Pro-NHEt9)-LHRH		/	Unkown
HY-P4447	(Des-Gly10,D-Pyr1,D-Leu6,Pro-NHEt9)-LHRH		/	Unkown
HY-P4456	(Des-His6)-ACTH (1-24) (human, bovine, rat)		/	Unkown
HY-P4459	(Des-Gly2)-Exenatide	Control	/	Unkown
HY-P4467	(Des-Pyr1,Des-Gly10,D-Leu6,Pro-NHEt9)-LHRH		/	Unkown
HY-P4541	(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14)	Antagonist	/	Unkown
HY-P4676A	Lys-(Des-Arg9,Leu8)-Bradykinin TFA	Antagonist	/	Unkown
HY-P5518	[Des-Arg10]-HOE I40	Antagonist	/	Unkown
HY-P5713	Des(8-14)brevinin-1PMa	Inhibitor	/	Unkown
HY-RS03703	DES Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-W706908	Des(isopropylamino) atenolol diol-d5		/	Unkown
HY-130562	DDA-tetracycline	Inhibitor	/	Unkown
HY-169836	Des-ethyl-carafiban		/	Unkown
HY-RS17101	Des Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS23545	Des Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-Z6430	Des-4-fluorobenzyl mosapride	Agonist	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	DES	MGD	MGI:94885
Canis familiaris	DES	VGNC	VGNC:39905
Rattus norvegicus	DES	RGD	RGD:620686
Bos taurus	DES	VGNC	VGNC:28013
Macaca mulatta	DES	VGNC	VGNC:71770
Felis catus	DES	VGNC	VGNC:61451
Others	DES	NCBI