1. PROTAC
  2. PROTAC Linker
  3. Amino-PEG11-amine

Amino-PEG11-amine 

Cat. No.: HY-130411
Handling Instructions

Amino-PEG11-amine, a PEG-based (12 units) PROTAC linker used to combine two mono diethylstilbestrol (DES)-based ligands, provides an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer.

For research use only. We do not sell to patients.

Amino-PEG11-amine Chemical Structure

Amino-PEG11-amine Chemical Structure

CAS No. : 479200-82-3

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Description

Amino-PEG11-amine, a PEG-based (12 units) PROTAC linker used to combine two mono diethylstilbestrol (DES)-based ligands, provides an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer[1].

IC50 & Target

PEGs

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Molecular Weight

544.68

Formula

C₂₄H₅₂N₂O₁₁

CAS No.

479200-82-3

SMILES

NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Amino-PEG11-aminePROTAC LinkerInhibitorinhibitorinhibit

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Amino-PEG11-amine
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HY-130411
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