1. PROTAC
  2. PROTAC Linkers
  3. Amino-PEG11-amine

Amino-PEG11-amine 

Cat. No.: HY-130411 Purity: ≥95.0%
Handling Instructions

Amino-PEG11-amine, a PEG-based (12 units) PROTAC linker used to combine two mono diethylstilbestrol (DES)-based ligands, provides an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer.

For research use only. We do not sell to patients.

Amino-PEG11-amine Chemical Structure

Amino-PEG11-amine Chemical Structure

CAS No. : 479200-82-3

Size Price Stock Quantity
50 mg USD 170 In-stock
Estimated Time of Arrival: December 31
100 mg USD 260 In-stock
Estimated Time of Arrival: December 31
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500 mg   Get quote  

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Description

Amino-PEG11-amine, a PEG-based (12 units) PROTAC linker used to combine two mono diethylstilbestrol (DES)-based ligands, provides an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer[1].

IC50 & Target

PEGs

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

544.68

Formula

C24H52N2O11

CAS No.
SMILES

NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

References
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Product Name:
Amino-PEG11-amine
Cat. No.:
HY-130411
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