Lbp - lipopolysaccharide binding protein Gene

Also Known as Ly88; Bpifd2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 16803

Summary

Enables lipopolysaccharide binding activity and signaling receptor binding activity. Involved in several processes, including positive regulation of respiratory burst involved in inflammatory response; positive regulation of tumor necrosis factor production; and response to bacterium. Acts upstream of or within several processes, including defense response to Gram-negative bacterium; leukocyte chemotaxis involved in inflammatory response; and positive regulation of neutrophil chemotaxis. Located in cell surface and extracellular space. Is expressed in brain; heart ventricle; liver lobe; and reproductive system. Orthologous to human LBP (lipopolysaccharide binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Lbp Products (1)

mRNA Protein Name
NM_008489.2 NP_032515.2 lipopolysaccharide-binding protein precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables lipopolysaccharide binding IDA
IDA: Inferred from direct assay
11079463 MGI
enables signaling receptor binding IDA
IDA: Inferred from direct assay
9338787 MGI
Biological Process GO Annotation Evidence Références Source
involved in acute-phase response IMP
IMP: Inferred from mutant phenotype
12932360 MGI
involved in cellular response to lipopolysaccharide IMP
IMP: Inferred from mutant phenotype
24380872 MGI
acts upstream of or within defense response to Gram-negative bacterium IMP
IMP: Inferred from mutant phenotype
12055258 MGI
involved in defense response to Gram-negative bacterium IMP
IMP: Inferred from mutant phenotype
9338787 MGI
involved in defense response to Gram-positive bacterium IMP
IMP: Inferred from mutant phenotype
12932360 MGI
involved in innate immune response IMP
IMP: Inferred from mutant phenotype
12932360 MGI
acts upstream of or within leukocyte chemotaxis involved in inflammatory response IMP
IMP: Inferred from mutant phenotype
12055258 MGI
involved in macrophage activation involved in immune response IDA
IDA: Inferred from direct assay
12932360 MGI
acts upstream of neutrophil chemotaxis IMP
IMP: Inferred from mutant phenotype
12055258 MGI
acts upstream of or within positive regulation of chemokine production IMP
IMP: Inferred from mutant phenotype
12055258 MGI
acts upstream of or within positive regulation of neutrophil chemotaxis IMP
IMP: Inferred from mutant phenotype
12055258 MGI
involved in positive regulation of respiratory burst involved in inflammatory response IMP
IMP: Inferred from mutant phenotype
9338787 MGI
involved in positive regulation of tumor necrosis factor production IDA
IDA: Inferred from direct assay
12932360 MGI
acts upstream of or within positive regulation of tumor necrosis factor production IMP
IMP: Inferred from mutant phenotype
12055258 MGI
involved in positive regulation of tumor necrosis factor production IMP
IMP: Inferred from mutant phenotype
9338787 MGI
acts upstream of or within response to lipopolysaccharide IMP
IMP: Inferred from mutant phenotype
12055258 MGI
involved in response to lipopolysaccharide IMP
IMP: Inferred from mutant phenotype
9338787 MGI
acts upstream of tumor necrosis factor production IMP
IMP: Inferred from mutant phenotype
12055258 MGI
Cellular Component GO Annotation Evidence Références Source
located in cell surface IDA
IDA: Inferred from direct assay
12932360 MGI
located in extracellular space IDA
IDA: Inferred from direct assay
9338787 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lipopolysaccharide-binding protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (16)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-141882 DC-LC3in-D5 Inhibitor 98.62% Unkown
HY-172476 DSPE-PEG2000-YIGSR 95.0% Unkown
HY-106010 LBP1 Agonist / Unkown
HY-155437 NEt-iFQ Agonist / Unkown
HY-172475 DSPE-PEG1000-YIGSR / Unkown
HY-172476A DSPE-PEG3400-YIGSR / Unkown
HY-172477 DSPE-PEG5000-YIGSR / Unkown
HY-P11772 LBP-14 / Unkown
HY-P11772A LBP-14-NH2 TFA Inhibitor 98.61% Unkown
HY-RS04226 EHHADH Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07543 LBP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07544 Lbp Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12272 RPSA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16804 Lbp Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18562 Ehhadh Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25044 Ehhadh Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lbp NCBI NCBI:3929