Acaa2 - acetyl-CoA acyltransferase 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 170465

Summary

Enables acetyl-CoA C-acyltransferase activity and acyl-CoA hydrolase activity. Involved in acetyl-CoA metabolic process and fatty acid beta-oxidation. Located in mitochondrial matrix. Orthologous to human ACAA2 (acetyl-CoA Acyltransferase 2). [provided by Alliance of Genome Resources, Apr 2022]

Acaa2 Products (1)

mRNA Protein Name
NM_130433.2 NP_569117.2 3-ketoacyl-CoA thiolase, mitochondrial

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables acetyl-CoA C-acyltransferase activity IDA
IDA: Inferred from direct assay
11879205 RGD
enables fatty acyl-CoA hydrolase activity IDA
IDA: Inferred from direct assay
16476568 RGD
Biological Process GO Annotation Evidence References Source
involved in acetyl-CoA metabolic process IDA
IDA: Inferred from direct assay
16476568 RGD
involved in fatty acid beta-oxidation IDA
IDA: Inferred from direct assay
11879205 RGD
Cellular Component GO Annotation Evidence References Source
located in mitochondrial matrix IDA
IDA: Inferred from direct assay
16476568 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

3-ketoacyl-CoA thiolase, mitochondrial

  • acetyl-CoA acetyltransferase

  • acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)

  • acyl-CoA hydrolase, mitochondrial

  • beta-ketothiolase

  • mitochondrial 3-oxoacyl-CoA thiolase

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-134377 Bocidelpar Modulator 98.08% Phase 2

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00118 ACAA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18647 Acaa2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25132 Acaa2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Acaa2 NCBI NCBI:10449