ABHD3 - abhydrolase domain containing 3, phospholipase Gene

Also Known as LABH3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 171586

About ABHD3

Cytogenetic location: 18q11.2 Genomic coordinates (GRCh38): 18:21,650,901-21,704,774 (from NCBI)

This gene has 10 transcripts (splice variants), 210 orthologues and 3 paralogues. Broad expression in colon (RPKM 25.3), small intestine (RPKM 19.0) and 23 other tissues.

Summary

This gene encodes a protein containing an alpha/beta hydrolase fold, which is a catalytic domain found in a very wide range of Enzymes. The function of this protein has not been determined. [provided by RefSeq, Jul 2008]

ABHD3 Products (3)

mRNA Protein Name
NM_001308256.2 NP_001295185.1 phospholipase ABHD3 isoform 2
NM_001308257.2 NP_001295186.1 phospholipase ABHD3 isoform 3
NM_138340.5 NP_612213.2 phospholipase ABHD3 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables phospholipase A1 activity IMP
IMP: Inferred from mutant phenotype
21926997 GOA
enables phospholipase A2 activity IMP
IMP: Inferred from mutant phenotype
21926997 GOA
Biological Process GO Annotation Evidence References Source
involved in phosphatidylcholine metabolic process IMP
IMP: Inferred from mutant phenotype
21926997 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ABHD3 Protein Structure

Abhydrolase_6

Abhydrolase_6: Alpha/beta hydrolase family (142 - 380)

  • 0
  • 100
  • 200
  • 300
  • 409 a.a.
Protein Preferred Names Protein Names

phospholipase ABHD3

  • abhydrolase domain-containing protein 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-164838 ABC47 Inhibitor 99.80% Unkown
HY-RS00094 ABHD3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris ABHD3 VGNC VGNC:37469
Felis catus ABHD3 VGNC VGNC:59485
Bos taurus ABHD3 VGNC VGNC:58350
Mus musculus ABHD3 MGD MGI:2147183
Macaca mulatta ABHD3 VGNC VGNC:69464
Rattus norvegicus ABHD3 RGD RGD:1310655
Others ABHD3 NCBI