2. Gene
  3. Mmp10 - matrix metallopeptidase 10 Gene

Mmp10 - matrix metallopeptidase 10 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as SL-2; MMP-10

Gene ID: 17384 | Gene type: protein coding

About Mmp10

Chromosome 9: 7,502,353-7,510,241 forward strand.GRCm39:CM001002.3

This gene has 1 transcript (splice variant), 417 orthologues, 23 paralogues and is associated with 4 phenotypes. Biased expression in large intestine adult (RPKM 4.9), duodenum adult (RPKM 2.4) and 2 other tissues.

Summary

This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprotein undergoes proteolytic processing to generate a mature, zinc-dependent endopeptidase Enzyme. The lack of encoded protein in mice promotes experimental lung Cancer formation, exacerbates experimental colitis and promotes development of inflammation-associated colonic dysplasia. This gene is located in a cluster of other matrix metalloproteinase genes on chromosome 9. [provided by RefSeq, Feb 2016]

Mmp10 Products(1)

mRNA Protein Name
NM_019471.3 NP_062344.1 stromelysin-2 preproprotein

Mmp10 Protein Structure

PG_binding_1

PG_binding_1: pfam01471 (32 - 86)

Peptidase_M10

Peptidase_M10: pfam00413 (107 - 263)

HX

HX: cd00094 (285 - 475)

  • 0
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  • 476 a.a.
Protein Preferred Names Protein Names

stromelysin-2

matrix metalloproteinase 10

transin-2

Related Agents

Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P2185A NFF-3 TFA Chemical 98.57% Unkown
HY-161285 MMP-9/10-IN-2 Inhibitor / Unkown
HY-P2185 NFF-3 Chemical / Unkown
HY-RS08518 MMP10 Human Pre-designed siRNA Set A / Unkown
HY-RS08519 Mmp10 Mouse Pre-designed siRNA Set A / Unkown
HY-RS08520 Mmp10 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mmp10 NCBI NCBI:4319