P2ry2 - purinergic receptor P2Y, G-protein coupled 2 Gene

Mus musculus

Also known as P2U1; P2Y2

Gene ID: 18442 | Gene type: protein coding

About P2ry2

Chromosome 7: 100,645,775-100,662,073 reverse strand.GRCm39:CM001000.3

This gene has 6 transcripts (splice variants), 201 orthologues, 13 paralogues and is associated with 4 phenotypes. Broad expression in heart adult (RPKM 12.3), small intestine adult (RPKM 1.9) and 18 other tissues.

Summary

Predicted to enable A1 Adenosine Receptor binding activity; ATP binding activity; and G protein-coupled UTP receptor activity. Acts upstream of or within positive regulation of mucus secretion. Predicted to be located in apical plasma membrane and basolateral plasma membrane. Predicted to colocalize with early endosome; lysosome; and mitochondrion. Orthologous to human P2RY2 (purinergic receptor P2Y2). [provided by Alliance of Genome Resources, Apr 2022]

P2ry2 Products(3)

mRNA	Protein	Name
NM_008773.4	NP_032799.2	P2Y purinoceptor 2
NM_001302346.1	NP_001289275.1	P2Y purinoceptor 2
NM_001302347.1	NP_001289276.1	P2Y purinoceptor 2

P2ry2 Protein Structure

7tmA_P2Y2

0
100
200
300
373 a.a.

Protein Preferred Names

Protein Names

P2Y purinoceptor 2

ATP receptor

P2U purinoceptor 1

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS09928	P2RY2 Human Pre-designed siRNA Set A	/	Unkown
HY-RS09929	P2ry2 Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS09930	P2ry2 Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	P2ry2	NCBI	NCBI:5029

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