Rbbp4 - retinoblastoma binding protein 4, chromatin remodeling factor Gene

Also Known as RBAP48; mRbAp48

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19646

Summary

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in chromatin organization. Predicted to act upstream of or within DNA replication and chromatin organization. Located in nucleus. Part of ESC/E(Z) complex and NuRD complex. Is expressed in several structures, including central nervous system; early conceptus; gonad; hemolymphoid system gland; and retina nuclear layer. Orthologous to human RBBP4 (RB binding protein 4, chromatin remodeling factor). [provided by Alliance of Genome Resources, Apr 2022]

Rbbp4 Products (1)

mRNA Protein Name
NM_009030.3 NP_033056.2 histone-binding protein RBBP4

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
28053041 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
14645126 MGI
Cellular Component GO Annotation Evidence References Source
part of ESC/E(Z) complex IDA
IDA: Inferred from direct assay
20064376 MGI
part of NuRD complex IDA
IDA: Inferred from direct assay
14645126 MGI
located in nucleus IDA
IDA: Inferred from direct assay
20720167 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

histone-binding protein RBBP4

  • CAF-1 p48 subunit

  • CAF-1 subunit C

  • CAF-I 48 kDa subunit

  • CAF-I p48

  • RBBP-4

  • chromatin assembly factor 1 subunit C

  • chromatin assembly factor I p48 subunit

  • nucleosome-remodeling factor subunit RBAP48

  • retinoblastoma-binding protein 4

  • retinoblastoma-bind

Recombinant Rbbp4 Proteins

Cat. No. Product Name Accession Purity
HY-P74600 RBBP4 Protein, Mouse (sf9, His) Q60972 (M1-S425) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P10600A BIMAX2 acetate Inhibitor 98.66% Unkown
HY-P10598 BIMAX1 / Unkown
HY-P10600 BIMAX2 Inhibitor / Unkown
HY-RS11716 RBBP4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18187 Rbbp4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24661 Rbbp4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rbbp4 NCBI NCBI:5928