S100b - S100 protein, beta polypeptide, neural Gene

Also Known as Bpb

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20203

Summary

Predicted to enable several functions, including RAGE receptor binding activity; S100 protein binding activity; and metal ion binding activity. Involved in learning or memory. Acts upstream of or within memory and regulation of neuronal synaptic plasticity. Located in cytoplasm; neuronal cell body; and nucleus. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; aspergillosis; and schizophrenia. Orthologous to human S100B (S100 calcium binding protein B). [provided by Alliance of Genome Resources, Apr 2022]

S100b Products (1)

mRNA Protein Name
NM_009115.3 NP_033141.1 protein S100-B

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in adaptive thermogenesis IDA
IDA: Inferred from direct assay
31043739 MGI
involved in learning or memory IMP
IMP: Inferred from mutant phenotype
11891290 MGI
acts upstream of or within memory IMP
IMP: Inferred from mutant phenotype
11891290 MGI
involved in neuron projection extension IDA
IDA: Inferred from direct assay
2592414 MGI
involved in positive regulation of neuron differentiation IDA
IDA: Inferred from direct assay
2592414 MGI
acts upstream of or within regulation of neuronal synaptic plasticity IMP
IMP: Inferred from mutant phenotype
11891290 MGI
involved in sympathetic neuron projection extension IDA
IDA: Inferred from direct assay
31043739 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
24582971 MGI
is active in extracellular region IDA
IDA: Inferred from direct assay
31043739 MGI
located in neuronal cell body IDA
IDA: Inferred from direct assay
15248193 MGI
located in nucleus IDA
IDA: Inferred from direct assay
15782413 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein S100-B

  • S-100 protein beta chain

  • S-100 protein subunit beta

  • S100 calcium-binding protein B

Recombinant S100b Proteins

Cat. No. Product Name Accession Purity
HY-P71276 S100B Protein, Mouse (His) P50114 (M1-E92) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-16918A Heptamidine dimethanesulfonate Inhibitor 99.12% Unkown
HY-16918 Heptamidine / Unkown
HY-RS12387 S100B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W237439 SEN205A Ligand / Unkown
HY-RS16975 S100b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23418 S100b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens S100b NCBI NCBI:6285