Selplg - selectin, platelet (p-selectin) ligand Gene

Also Known as CD162; Psgl1; Selp1; Selpl; Psgl-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20345

Summary

Involved in leukocyte adhesive activation. Acts upstream of or within leukocyte tethering or rolling. Predicted to be located in plasma membrane raft and uropod. Predicted to be active in plasma membrane. Is expressed in brain and thymus primordium. Human ortholog(s) of this gene implicated in carotid artery disease. Orthologous to human SELPLG (Selectin P ligand). [provided by Alliance of Genome Resources, Apr 2022]

Selplg Products (1)

mRNA Protein Name
NM_009151.3 NP_033177.3 P-selectin glycoprotein ligand 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
11238599 MGI
Biological Process GO Annotation Evidence References Source
involved in leukocyte adhesive activation IMP
IMP: Inferred from mutant phenotype
17632516 MGI
acts upstream of or within leukocyte tethering or rolling IMP
IMP: Inferred from mutant phenotype
15956287 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

P-selectin glycoprotein ligand 1

  • selectin P ligand

Recombinant Selplg Proteins

Cat. No. Product Name Accession Purity
HY-P7800 CD162/PSGL-1 Protein, Mouse (HEK293, Fc) CAA62583.1 (Q42-C307) ≥ 90%, as determined by reducing SDS-PAGE.
HY-P77165 CD162/PSGL-1 Protein, Mouse (HEK293) Q62170 (L18-C307) ≥ 85%, as determined by reducing SDS-PAGE.
HY-P700816 CD162/PSGL-1 Protein, Mouse (HEK293, His) Q62170 (Q42-C307) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12648 SELPLG Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18203 Selplg Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24679 Selplg Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Selplg NCBI NCBI:6404