Slc2a3 - solute carrier family 2 (facilitated glucose transporter), member 3 Gene

Also Known as Glut3; Glut-3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20527

About Slc2a3

Chromosome 6: 122,704,768-122,778,599 reverse strand.GRCm39:CM000999.3

This gene has 8 transcripts (splice variants), 254 orthologues, 11 paralogues and is associated with 9 phenotypes. Biased expression in testis adult (RPKM 213.3), placenta adult (RPKM 31.) and 5 other tissues.

Summary

Enables D-glucose transmembrane transporter activity and dehydroascorbic acid transmembrane transporter activity. Involved in dehydroascorbic acid transport and glucose transmembrane transport. Located in acrosomal membrane and plasma membrane. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; early conceptus; and reproductive system. Orthologous to several human genes including SLC2A3 (solute carrier family 2 member 3). [provided by Alliance of Genome Resources, Apr 2022]

Slc2a3 Products (8)

mRNA Protein Name
NM_001410375.1 NP_001397304.1 solute carrier family 2, facilitated glucose transporter member 3 isoform a
NM_001410377.1 NP_001397306.1 solute carrier family 2, facilitated glucose transporter member 3 isoform a
NM_011401.5 NP_035531.3 solute carrier family 2, facilitated glucose transporter member 3 isoform b
NM_001410376.1 NP_001397305.1 solute carrier family 2, facilitated glucose transporter member 3 isoform a
NM_001410372.1 NP_001397301.1 solute carrier family 2, facilitated glucose transporter member 3 isoform d
NM_001410374.1 NP_001397303.1 solute carrier family 2, facilitated glucose transporter member 3 isoform d
NM_001410378.1 NP_001397307.1 solute carrier family 2, facilitated glucose transporter member 3 isoform a
NM_001410371.1 NP_001397300.1 solute carrier family 2, facilitated glucose transporter member 3 isoform c

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables D-glucose transmembrane transporter activity IDA
IDA: Inferred from direct assay
18668520 MGI
enables dehydroascorbic acid transmembrane transporter activity IDA
IDA: Inferred from direct assay
18668520 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
35810171 MGI
Biological Process GO Annotation Evidence References Source
involved in D-glucose transmembrane transport IDA
IDA: Inferred from direct assay
18668520 MGI
acts upstream of or within D-glucose transmembrane transport IMP
IMP: Inferred from mutant phenotype
17213475 MGI
involved in dehydroascorbic acid transport IDA
IDA: Inferred from direct assay
18668520 MGI
Cellular Component GO Annotation Evidence References Source
located in acrosomal membrane IDA
IDA: Inferred from direct assay
19144954 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
18668520 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
18668520 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Slc2a3 Protein Structure

MFS_GLUT_Class1

MFS_GLUT_Class1: cd17431 (11 - 455)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 493 a.a.
Protein Preferred Names Protein Names

solute carrier family 2, facilitated glucose transporter member 3

  • glucose transporter type 3, brain

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13167 SLC2A3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13168 Slc2a3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13169 SLC2A3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc2a3 NCBI NCBI:6515