Ssb - small RNA binding exonuclease protection factor La Gene

Also Known as SS-B

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20823

Summary

Enables RNA binding activity. Predicted to be involved in several processes, including IRES-dependent viral translational initiation; RNA metabolic process; and protein localization to cytoplasmic stress granule. Located in nucleus. Is expressed in several structures, including central nervous system; early conceptus; gonad; sensory organ; and spleen. Orthologous to human SSB (small RNA binding exonuclease protection factor La). [provided by Alliance of Genome Resources, Apr 2022]

Ssb Products (3)

mRNA Protein Name
NM_001110145.1 NP_001103615.1 lupus La protein homolog isoform a
NM_001355265.1 NP_001342194.1 lupus La protein homolog isoform b
NM_009278.4 NP_033304.1 lupus La protein homolog isoform a

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables RNA binding IDA
IDA: Inferred from direct assay
17971306 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
11817591 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lupus La protein homolog

  • La protein

  • Lupus LA protein homolog (LA ribonucleoprotein) (LA autoantigen homolog)

  • Sjogren syndrome antigen B

  • autoantigen La

  • la autoantigen homolog

  • la ribonucleoprotein

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-10617A Rucaparib Inhibitor 99.96% Yes
HY-10617 Rucaparib phosphate Inhibitor 99.76% Yes
HY-102003 Rucaparib monocamsylate Inhibitor 99.91% Yes
HY-102003A Rucaparib camsylate Inhibitor / Unkown

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-145804 Palacaparib Inhibitor 98.30% Phase 2

Pre-clinical Phase

Bioactive Molecules (11)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-137457 Venadaparib Inhibitor 98.11% Unkown
HY-122891A (2S)-SB02024 Inhibitor 98.14% Unkown
HY-105510 Hydroxyrubicin / Unkown
HY-10617AS1 Rucaparib-d3 Inhibitor / Unkown
HY-132267S N-Nitrosodibenzylamine-d4 Inhibitor / Unkown
HY-172154 SSB-2548 / Unkown
HY-RS13804 SSB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W703958 N-Nitrosodibenzylamine-d10 / Unkown
HY-RS17122 Ssb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23567 Ssb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W159870 N-Nitrosodibenzylamine Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ssb NCBI NCBI:6741