Ido2 - indoleamine 2,3-dioxygenase 2 Gene

Also Known as Ido-2; Indol1; C230043N17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 209176

About Ido2

Chromosome 8: 25,021,908-25,066,349 reverse strand.GRCm39:CM001001.3

This gene has 4 transcripts (splice variants), 91 orthologues and is associated with 7 phenotypes. Biased expression in liver adult (RPKM 13.5), genital fat pad adult (RPKM 2.6) and 1 other tissue.

Summary

Enables indoleamine 2,3-dioxygenase activity. Acts upstream of or within tryptophan catabolic process to kynurenine. Located in cytoplasm. Is expressed in corpus striatum. Orthologous to human IDO2 (indoleamine 2,3-dioxygenase 2). [provided by Alliance of Genome Resources, Apr 2022]

Ido2 Products (1)

mRNA Protein Name
NM_145949.2 NP_666061.3 indoleamine 2,3-dioxygenase 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables indoleamine 2,3-dioxygenase activity IDA
IDA: Inferred from direct assay
17499941 MGI
enables indoleamine 2,3-dioxygenase activity IMP
IMP: Inferred from mutant phenotype
17671174 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within tryptophan catabolic process to kynurenine IDA
IDA: Inferred from direct assay
17499941 MGI
acts upstream of or within tryptophan catabolic process to kynurenine IMP
IMP: Inferred from mutant phenotype
17671174 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
17671174 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Ido2 Protein Structure

IDO

IDO: pfam01231 (14 - 398)

  • 0
  • 100
  • 200
  • 300
  • 405 a.a.
Protein Preferred Names Protein Names

indoleamine 2,3-dioxygenase 2

  • indoleamine 2,3-dioxygenase-like protein 1

  • indoleamine-pyrrole 2,3 dioxygenase-like 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-100687 GNF-PF-3777 Inhibitor 98.03% Unkown
HY-145280 IDO1/2-IN-1 Inhibitor 98.06% Unkown
HY-151093 IDO2-IN-1 Inhibitor 98.10% Unkown
HY-112867 Amg-1 Inhibitor / Unkown
HY-184078 8-F-2-(Me-Pip-Me)-Tryptanthrin Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ido2 NCBI NCBI:169355