Amg-1
Based on 1 Customer Validation
Amg-1 is a potent, reversible and selective indoleamine 2,3-dioxygenase (IDO1) inhibitor (IC50 = 3.0 μM). Amg-1 exhibits >80-fold selectivity over IDO2 (IC50 > 250 μM) and >20-fold selective over TDO (IC50 > 62.5 μM). Amg-1 can be used for cancer, hypotension, and neurological disorders research.
For research use only. We do not sell to patients.
- CAS No.: 496023-55-3
- Formula: C20H16N4O3S2
- Molecular Weight:424.50
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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IDO1 3.0 μM (IC50) |
IDO2 >250 μM (IC50) |
TDO >62.5 μM (IC50) |
Chemical Information
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CAS No. 496023-55-3
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Appearance Solid
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Molecular Weight 424.50
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Formula C20H16N4O3S2
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Color Light brown to brown
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SMILES
O=C(NC1=CC=C(OCO2)C2=C1)CSC3=NN=C4N3C(C5=CC=C(C)C=C5)=CS4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)