Trmt1 - tRNA methyltransferase 1 Gene

Also Known as 6720477L24; D8Ertd812e; 6720406L13Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 212528

Summary

Predicted to enable tRNA (guanine-N2-)-methyltransferase activity. Predicted to be involved in tRNA N2-guanine methylation. Predicted to act upstream of or within methylation and tRNA processing. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human TRMT1 (tRNA methyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

Trmt1 Products (5)

mRNA Protein Name
NM_001164559.1 NP_001158031.1 tRNA (guanine(26)-N(2))-dimethyltransferase isoform 1
NM_001164560.1 NP_001158032.1 tRNA (guanine(26)-N(2))-dimethyltransferase isoform 2
NM_001364175.1 NP_001351104.1 tRNA (guanine(26)-N(2))-dimethyltransferase isoform 3
NM_001364176.1 NP_001351105.1 tRNA (guanine(26)-N(2))-dimethyltransferase isoform 4
NM_198020.2 NP_932137.2 tRNA (guanine(26)-N(2))-dimethyltransferase isoform 1
Protein Preferred Names Protein Names

tRNA (guanine(26)-N(2))-dimethyltransferase

  • TRM1 tRNA methyltransferase 1 homolog

  • n(2),N(2)-dimethylguanosine tRNA methyltransferase

  • tRNA 2,2-dimethylguanosine-26 methyltransferase

  • tRNA(guanine-26,N(2)-N(2)) methyltransferase

  • tRNA(m(2,2)G26)dimethyltransferase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-153141 MP-1 Ligand / Unkown
HY-RS15086 TRMT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15097 TRMU Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19490 Trmt1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25984 Trmt1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trmt1 NCBI NCBI:55621