Llgl2 - LLGL2 scribble cell polarity complex component Gene

Also Known as Llglh2; 9130006H11Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 217325

Summary

Predicted to enable GTPase activator activity; PDZ domain binding activity; and Myosin II binding activity. Acts upstream of or within establishment or maintenance of polarity of embryonic epithelium; labyrinthine layer development; and post-embryonic development. Predicted to be located in cytosol and intracellular membrane-bounded organelle. Predicted to be active in cortical actin Cytoskeleton and plasma membrane. Is expressed in several structures, including cardiovascular system; endocrine gland; genitourinary system; gut; and nasal cavity epithelium. Orthologous to human LLGL2 (LLGL scribble cell polarity complex component 2). [provided by Alliance of Genome Resources, Apr 2022]

Llgl2 Products (2)

mRNA Protein Name
NM_001252532.1 NP_001239461.1 LLGL scribble cell polarity complex component 2 isoform 2
NM_145438.2 NP_663413.2 LLGL scribble cell polarity complex component 2 isoform 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within branching involved in labyrinthine layer morphogenesis IMP
IMP: Inferred from mutant phenotype
21606200 MGI
acts upstream of or within establishment or maintenance of polarity of embryonic epithelium IMP
IMP: Inferred from mutant phenotype
21606200 MGI
acts upstream of or within labyrinthine layer blood vessel development IMP
IMP: Inferred from mutant phenotype
21606200 MGI
acts upstream of or within multicellular organism growth IMP
IMP: Inferred from mutant phenotype
21606200 MGI
acts upstream of or within placenta development IMP
IMP: Inferred from mutant phenotype
21606200 MGI
acts upstream of or within post-embryonic development IMP
IMP: Inferred from mutant phenotype
21606200 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

LLGL scribble cell polarity complex component 2

  • lethal giant larvae-like protein 2

  • lethal(2) giant larvae protein homolog 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07701 LLGL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22611 Llgl2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29126 Llgl2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Llgl2 NCBI NCBI:3993