Nr2c2 - nuclear receptor subfamily 2, group C, member 2 Gene

Also Known as Tr4; TAK1; mKIAA4145

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22026

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and nuclear receptor activity. Involved in several processes, including cerebellum development; positive regulation of embryonic development; and positive regulation of myoblast differentiation. Acts upstream of or within several processes, including lipopolysaccharide-mediated signaling pathway; p38MAPK cascade; and spermatogenesis. Predicted to be located in nucleoplasm. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human NR2C2 (nuclear receptor subfamily 2 group C member 2). [provided by Alliance of Genome Resources, Apr 2022]

Nr2c2 Products (10)

mRNA Protein Name
NM_001347342.2 NP_001334271.1 nuclear receptor subfamily 2 group C member 2 isoform 1
NM_001410478.1 NP_001397407.1 nuclear receptor subfamily 2 group C member 2 isoform 1
NM_001410479.1 NP_001397408.1 nuclear receptor subfamily 2 group C member 2 isoform 2
NM_001410480.1 NP_001397409.1 nuclear receptor subfamily 2 group C member 2 isoform 2
NM_001410481.1 NP_001397410.1 nuclear receptor subfamily 2 group C member 2 isoform 2
NM_001410482.1 NP_001397411.1 nuclear receptor subfamily 2 group C member 2 isoform 2
NM_001410483.1 NP_001397412.1 nuclear receptor subfamily 2 group C member 2 isoform 3
NM_001410484.1 NP_001397413.1 nuclear receptor subfamily 2 group C member 2 isoform 3
NM_001410485.1 NP_001397414.1 nuclear receptor subfamily 2 group C member 2 isoform 3
NM_011630.4 NP_035760.1 nuclear receptor subfamily 2 group C member 2 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19268530 MGI
Biological Process GO Annotation Evidence References Source
involved in cerebellum development IMP
IMP: Inferred from mutant phenotype
20393820 MGI
acts upstream of or within lipopolysaccharide-mediated signaling pathway IMP
IMP: Inferred from mutant phenotype
9851930 MGI
acts upstream of or within meiotic cell cycle IMP
IMP: Inferred from mutant phenotype
15199144 MGI
involved in p38MAPK cascade IEP
IEP: Inferred from expression pattern
22337877 MGI
involved in positive regulation of behavior IMP
IMP: Inferred from mutant phenotype
20393820 MGI
involved in positive regulation of embryonic development IMP
IMP: Inferred from mutant phenotype
19131575 MGI
involved in positive regulation of myoblast differentiation IDA
IDA: Inferred from direct assay
22337877 MGI
acts upstream of or within spermatogenesis IMP
IMP: Inferred from mutant phenotype
15199144 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nuclear receptor subfamily 2 group C member 2

  • nuclear receptor subfamily 2, group H, member 2

  • orphan nuclear receptor TAK1

  • orphan nuclear receptor TR4

  • orphan receptor, TR4

  • testicular receptor 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09537 NR2C2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-118574 UBP141 Antagonist / Unkown
HY-RS09538 NR2C2AP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22687 Nr2c2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29201 Nr2c2 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nr2c2 NCBI NCBI:7182