Trpc3 - transient receptor potential cation channel, subfamily C, member 3 Gene

Also Known as Mwk; Trp3; Trcp3; Trrp3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22065

Summary

Predicted to enable calcium activated cation channel activity; inositol 1,4,5 trisphosphate binding activity; and store-operated Calcium Channel activity. Predicted to be involved in several processes, including metal ion transport; positive regulation of cardiac muscle hypertrophy in response to stress; and response to ATP. Predicted to act upstream of or within calcium ion transport. Predicted to be located in plasma membrane. Predicted to be part of cation channel complex. Predicted to be integral component of plasma membrane. Is expressed in cochlea; ganglia; limb; spinal cord; and trunk somite. Human ortholog(s) of this gene implicated in cerebellar ataxia type 41. Orthologous to human TRPC3 (transient receptor potential cation channel subfamily C member 3). [provided by Alliance of Genome Resources, Apr 2022]

Trpc3 Products (2)

mRNA Protein Name
NM_001403842.1 NP_001390771.1 short transient receptor potential channel 3 isoform 2
NM_019510.3 NP_062383.2 short transient receptor potential channel 3 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
19812035 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

short transient receptor potential channel 3

  • TRP-3

  • mTrp3

  • receptor-activated cation channel TRP3

  • transient receptor protein 3

  • trp-related protein 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (10)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-111098 GSK1702934A Agonist 99.52% Unkown
HY-19408 Pyr10 Inhibitor 99.95% Unkown
HY-101795 Larixyl acetate Inhibitor 99.44% Unkown
HY-133012 GFB-8438 Inhibitor 99.74% Unkown
HY-108464A Phenamil methanesulfonate Inhibitor 98.1% Unkown
HY-161766 L687 Activator 99.49% Unkown
HY-138668 JW-65 Inhibitor 99.05% Unkown
HY-147357 TRPC3/6-IN-1 Inhibitor 99.20% Unkown
HY-179489 TRPC3 agonist-1 Agonist 99.95% Unkown
HY-162090 TRPC antagonist 1 Antagonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trpc3 NCBI NCBI:7222