MMD2 - monocyte to macrophage differentiation associated 2 Gene

Also Known as PAQR10

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 221938

Summary

This gene encodes a member of the PAQR (progestin and adipoQ receptor) family. Members of this family are evolutionarily conserved with significant sequence identity to Bacterial hemolysin-like proteins and are defined by a set of seven transmembrane domains. The protein encoded by this gene localizes to the Golgi apparatus to modulate Ras signaling. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jun 2012]

MMD2 Products (3)

mRNA Protein Name
NM_001100600.2 NP_001094070.1 monocyte to macrophage differentiation factor 2 isoform 1
NM_001270375.2 NP_001257304.1 monocyte to macrophage differentiation factor 2 isoform 3
NM_198403.4 NP_940685.3 monocyte to macrophage differentiation factor 2 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
enables protein kinase activity IDA
IDA: Inferred from direct assay
21968647 GOA
Biological Process GO Annotation Evidence References Source
involved in positive regulation of Ras protein signal transduction IDA
IDA: Inferred from direct assay
21968647 GOA
involved in positive regulation of neuron differentiation IDA
IDA: Inferred from direct assay
21968647 GOA
involved in positive regulation of protein kinase activity IDA
IDA: Inferred from direct assay
21968647 GOA
involved in regulation of protein localization IDA
IDA: Inferred from direct assay
21968647 GOA
Cellular Component GO Annotation Evidence References Source
located in Golgi membrane IDA
IDA: Inferred from direct assay
22339580 GOA
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
22500632 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

monocyte to macrophage differentiation factor 2

  • monocyte-to-macrophage differentiation-associated protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08512 MMD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown