Urod - uroporphyrinogen decarboxylase Gene

Also Known as UPD; Uro-d

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22275

Summary

This gene encodes an enzyme that catalyzes the conversion of uroporphyrinogen-III to coproporphyrinogen-III, an intermediate step in heme biosynthesis. Homozygous knockout mice for this gene exhibit embryonic lethality. [provided by RefSeq, Aug 2015]

Urod Products (1)

mRNA Protein Name
NM_009478.4 NP_033504.2 uroporphyrinogen decarboxylase

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables uroporphyrinogen decarboxylase activity IDA
IDA: Inferred from direct assay
8661721 MGI
enables uroporphyrinogen decarboxylase activity IMP
IMP: Inferred from mutant phenotype
11134514 MGI
Biological Process GO Annotation Evidence References Source
involved in heme A biosynthetic process IMP
IMP: Inferred from mutant phenotype
17360334 MGI
involved in heme B biosynthetic process IMP
IMP: Inferred from mutant phenotype
17360334 MGI
involved in heme O biosynthetic process IMP
IMP: Inferred from mutant phenotype
17360334 MGI
acts upstream of or within heme biosynthetic process IMP
IMP: Inferred from mutant phenotype
17360334 MGI
acts upstream of or within heme metabolic process IMP
IMP: Inferred from mutant phenotype
11134514 MGI
Cellular Component GO Annotation Evidence References Source
is active in cytosol IDA
IDA: Inferred from direct assay
12297827 MGI
located in cytosol IDA
IDA: Inferred from direct assay
17360334 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

uroporphyrinogen decarboxylase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15509 UROD Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21453 Urod Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27971 Urod Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Urod NCBI NCBI:7389