Adgrf5 - adhesion G protein-coupled receptor F5 Gene

Also Known as Gpr116; mKIAA0758; 9330185D23; 8430401C09Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 224792

Summary

Predicted to enable G protein-coupled receptor activity. Acts upstream of or within several processes, including glomerular filtration; pharyngeal arch artery morphogenesis; and surfactant homeostasis. Located in apical part of cell. Is expressed in several structures, including genitourinary system; immune system; liver and biliary system; lung; and spinal cord vascular element. Orthologous to human ADGRF5 (adhesion G protein-coupled receptor F5). [provided by Alliance of Genome Resources, Apr 2022]

Adgrf5 Products (8)

mRNA Protein Name
NM_001081178.2 NP_001074647.1 adhesion G protein-coupled receptor F5 isoform 1 precursor
NM_001357332.1 NP_001344261.1 adhesion G protein-coupled receptor F5 isoform 2 precursor
NM_001404529.1 NP_001391458.1 adhesion G protein-coupled receptor F5 isoform 3 precursor
NM_001404530.1 NP_001391459.1 adhesion G protein-coupled receptor F5 isoform 3 precursor
NM_001404536.1 NP_001391465.1 adhesion G protein-coupled receptor F5 isoform 4 precursor
NM_001404541.1 NP_001391470.1 adhesion G protein-coupled receptor F5 isoform 5 precursor
NM_001404546.1 NP_001391475.1 adhesion G protein-coupled receptor F5 isoform 6 precursor
NM_001404548.1 NP_001391477.1 adhesion G protein-coupled receptor F5 isoform 2 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within energy reserve metabolic process IMP
IMP: Inferred from mutant phenotype
22971422 MGI
acts upstream of or within erythrocyte development IGI
IGI: Inferred from genetic interaction
28806758 MGI
acts upstream of or within fat cell differentiation IMP
IMP: Inferred from mutant phenotype
22971422 MGI
acts upstream of or within glomerular filtration IGI
IGI: Inferred from genetic interaction
28806758 MGI
acts upstream of or within glucose homeostasis IMP
IMP: Inferred from mutant phenotype
22971422 MGI
acts upstream of macrophage activation IMP
IMP: Inferred from mutant phenotype
25778400 MGI
acts upstream of or within negative regulation of macrophage activation IMP
IMP: Inferred from mutant phenotype
25778400 MGI
acts upstream of or within pharyngeal arch artery morphogenesis IGI
IGI: Inferred from genetic interaction
28806758 MGI
acts upstream of phospholipid biosynthetic process IMP
IMP: Inferred from mutant phenotype
23590306 MGI
acts upstream of or within positive regulation of phospholipid biosynthetic process IMP
IMP: Inferred from mutant phenotype
23590306 MGI
acts upstream of or within regulation of lipid metabolic process IMP
IMP: Inferred from mutant phenotype
22971422 MGI
acts upstream of or within surfactant homeostasis IMP
IMP: Inferred from mutant phenotype
23590306 MGI
involved in surfactant homeostasis IMP
IMP: Inferred from mutant phenotype
23590306 MGI
Cellular Component GO Annotation Evidence References Source
located in apical part of cell IDA
IDA: Inferred from direct assay
23590306 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

adhesion G protein-coupled receptor F5

  • G protein coupled receptor Gpr116

  • G protein-coupled receptor 116

  • probable G-protein coupled receptor 116

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P3942 SDP116 Inhibitor 98.26% Unkown
HY-RS00353 ADGRF5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21816 Adgrf5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adgrf5 NCBI NCBI:221395