Zfp36 - zinc finger protein 36 Gene

Also Known as Ttp; Gos24; TISII; Tis11; Nup475; TIS11D; Zfp-36

Species: Mus musculus

Gene Type: protein coding
Gene ID: 22695

Summary

Enables 14-3-3 protein binding activity; RNA polymerase binding activity; and mRNA 3'-UTR AU-rich region binding activity. Involved in several processes, including negative regulation of polynucleotide adenylyltransferase activity; p38MAPK cascade; and regulation of gene expression. Acts upstream of or within several processes, including negative regulation of inflammatory response; negative regulation of myeloid cell differentiation; and regulation of RNA metabolic process. Located in cytosol and nucleus. Part of CCR4-NOT complex and ribonucleoprotein complex. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and hemolymphoid system gland. Used to study rheumatoid arthritis. Orthologous to human ZFP36 (ZFP36 ring finger protein). [provided by Alliance of Genome Resources, Apr 2022]

Zfp36 Products (1)

mRNA Protein Name
NM_011756.4 NP_035886.1 mRNA decay activator protein ZFP36
Protein Preferred Names Protein Names

mRNA decay activator protein ZFP36

  • TPA-induced sequence 11

  • growth factor-inducible nuclear protein NUP475

  • tristetraprolin

  • tristetraproline

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16040 ZFP36 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16042 ZFP36L2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16041 ZFP36L1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18557 Zfp36 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20661 Zfp36l2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21270 Zfp36l1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25039 Zfp36 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27172 Zfp36l2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27788 Zfp36l1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Zfp36 NCBI NCBI:7538