ACSBG1 - acyl-CoA synthetase bubblegum family member 1 Gene

Also Known as BG; BG1; BGM; LPD; GR-LACS

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 23205

About ACSBG1

Cytogenetic location: 15q25.1 Genomic coordinates (GRCh38): 15:78,167,468-78,234,565 (from NCBI)

This gene has 14 transcripts (splice variants), 228 orthologues and 12 paralogues. Ubiquitous expression in brain (RPKM 8.4), adrenal (RPKM 6.3) and 25 other tissues.

Summary

The protein encoded by this gene possesses long-chain acyl-CoA synthetase activity. It is thought to play a central role in brain very long-chain fatty acids metabolism and myelinogenesis. [provided by RefSeq, Jul 2008]

ACSBG1 Products (2)

mRNA Protein Name
NM_001199377.2 NP_001186306.1 long-chain-fatty-acid--CoA ligase ACSBG1 isoform 2
NM_015162.5 NP_055977.3 long-chain-fatty-acid--CoA ligase ACSBG1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables long-chain fatty acid-CoA ligase activity IDA
IDA: Inferred from direct assay
10954726 GOA
enables very long-chain fatty acid-CoA ligase activity IDA
IDA: Inferred from direct assay
10954726 GOA
Biological Process GO Annotation Evidence References Source
involved in long-chain fatty acid metabolic process IDA
IDA: Inferred from direct assay
10954726 GOA
involved in very long-chain fatty acid metabolic process IDA
IDA: Inferred from direct assay
10954726 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
10954726 GOA
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
24269233 GOA
located in plasma membrane IDA
IDA: Inferred from direct assay
24269233 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

long-chain-fatty-acid--CoA ligase ACSBG1

  • bubblegum

Related Diseases

Diseases Alias
Epilepsy, Idiopathic Generalized 13

  • Epilepsy, Childhood Absence 4

  • EIG13

  • Epilepsy, Idiopathic Generalized, Susceptibility To, 13

  • Epilepsy, Childhood Absence, Susceptibility To, 4

  • Idiopathic Generalized Epilepsy 13

  • Epilepsy, Juvenile Myoclonic, Susceptibility To, 5

  • Epilepsy, Juvenile Myoclonic 5

  • ECA4

  • Juvenile Myoclonic Epilepsy 5

  • EJM5

  • Susceptibility To Juvenile Myoclonic Epilepsy 5

  • Epilepsy, Idiopathic, Generalized, Susceptibility To, Type 13
Vulvar Leiomyosarcoma
Adrenoleukodystrophy

  • X-Linked Adrenoleukodystrophy

  • ALD

  • Siemerling-Creutzfeldt Disease

  • X-Ald

  • X-Linked Cerebral Adrenoleukodystrophy

  • Bronze Schilder Disease

  • Melanodermic Leukodystrophy

  • Addison Disease And Cerebral Sclerosis

  • Adrenomyeloneuropathy, Adult

  • Diffuse Sclerosis

  • X-Cald

  • Adrenomyeloneuropathy

  • Encephalitis Periaxialis Concentrica

  • Encephalitis Periaxialis, Schilder'S

  • Sudanophilic Cerebral Sclerosis

  • Ald Childhood Cerebral Form

  • Adrenoleukodystrophy X-Linked Cerebral Form

  • Adrenoleukodystrophy Childhood Cerebral Form

  • Childhood Cerebral Ald

  • Schilder Disease

  • X-Linked Ald

  • Adrenoleukodystrophy, X-Linked

  • Amn

  • Diffuse Cerebral Sclerosis Of Schilder

  • Systemic Scleroderma

  • Balo'S Concentric Sclerosis

  • Ald - [Adrenoleukodystrophy]

  • Addison-Schilder
Vulvar Sarcoma

  • Sarcoma Of Vulva

  • Vulva Sarcoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00196 ACSBG1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus ACSBG1 VGNC VGNC:25560
Felis catus ACSBG1 VGNC VGNC:59531
Macaca mulatta ACSBG1 VGNC VGNC:69547
Rattus norvegicus ACSBG1 RGD RGD:708557
Mus musculus ACSBG1 MGD MGI:2385656
Canis familiaris ACSBG1 VGNC VGNC:37529
Others ACSBG1 NCBI