RPRD2 - regulation of nuclear pre-mRNA domain containing 2 Gene

Also Known as HSPC099; KIAA0460

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 23248

About RPRD2

Cytogenetic location: 1q21.2 Genomic coordinates (GRCh38): 1:150,364,147-150,476,566 (from NCBI)

This gene has 4 transcripts (splice variants), 271 orthologues and 2 paralogues. Ubiquitous expression in thyroid (RPKM 11.1), ovary (RPKM 10.9) and 25 other tissues.

Summary

Predicted to enable RNA polymerase II complex binding activity. Predicted to be involved in mRNA 3'-end processing. Part of RNA polymerase II, holoenzyme. [provided by Alliance of Genome Resources, Apr 2022]

RPRD2 Products (14)

mRNA Protein Name
NM_001297673.2 NP_001284602.1 regulation of nuclear pre-mRNA domain-containing protein 2 isoform 2
NM_001297674.2 NP_001284603.1 regulation of nuclear pre-mRNA domain-containing protein 2 isoform 3
NM_001387114.1 NP_001374043.1 regulation of nuclear pre-mRNA domain-containing protein 2 isoform 4
NM_001387115.1 NP_001374044.1 regulation of nuclear pre-mRNA domain-containing protein 2 isoform 5
NM_001387116.1 NP_001374045.1 regulation of nuclear pre-mRNA domain-containing protein 2 isoform 6
NM_001387117.1 NP_001374046.1 regulation of nuclear pre-mRNA domain-containing protein 2 isoform 7
NM_001387118.1 NP_001374047.1 regulation of nuclear pre-mRNA domain-containing protein 2 isoform 8
NM_001387119.1 NP_001374048.1 regulation of nuclear pre-mRNA domain-containing protein 2 isoform 9
NM_001387120.1 NP_001374049.1 regulation of nuclear pre-mRNA domain-containing protein 2 isoform 10
NM_001387121.1 NP_001374050.1 regulation of nuclear pre-mRNA domain-containing protein 2 isoform 11
NM_001387122.1 NP_001374051.1 regulation of nuclear pre-mRNA domain-containing protein 2 isoform 12
NM_001387123.1 NP_001374052.1 regulation of nuclear pre-mRNA domain-containing protein 2 isoform 13
NM_001387124.1 NP_001374053.1 regulation of nuclear pre-mRNA domain-containing protein 2 isoform 13
NM_015203.5 NP_056018.2 regulation of nuclear pre-mRNA domain-containing protein 2 isoform 1

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
part of transcription preinitiation complex IDA
IDA: Inferred from direct assay
22231121 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RPRD2 Protein Structure

CTD_bind

CTD_bind: RNA polymerase II-binding domain. (74 - 134)

  • 0
  • 300
  • 600
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  • 1200
  • 1461 a.a.
Protein Preferred Names Protein Names

regulation of nuclear pre-mRNA domain-containing protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12218 RPRD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus RPRD2 MGD MGI:1922387
Macaca mulatta RPRD2 VGNC VGNC:77121
Rattus norvegicus RPRD2 RGD RGD:2320792
Felis catus RPRD2 VGNC VGNC:64750
Canis familiaris RPRD2 VGNC VGNC:45728
Bos taurus RPRD2 VGNC VGNC:34128
Others RPRD2 NCBI