Iapp - islet amyloid polypeptide Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24476

Summary

Predicted to enable identical protein binding activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway; Amylin Receptor signaling pathway; and eating behavior. Predicted to be located in inclusion body and neuronal cell body. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus and type 2 diabetes mellitus. Orthologous to human IAPP (islet amyloid polypeptide). [provided by Alliance of Genome Resources, Apr 2022]

Iapp Products (1)

mRNA Protein Name
NM_012586.3 NP_036718.1 islet amyloid polypeptide preproprotein

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway IGI
IGI: Inferred from genetic interaction
22500019 RGD
involved in amylin receptor signaling pathway IGI
IGI: Inferred from genetic interaction
22500019 RGD
involved in eating behavior IMP
IMP: Inferred from mutant phenotype
15130879 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

islet amyloid polypeptide

  • DAP

  • amylin

  • diabetes-associated peptide

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (10)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P2392 Fmoc-Ala-Thr(psi(Me,Me)pro)-OH / Unkown
HY-P4767 Amylin (1-13) (human) Ligand 98.23% Unkown
HY-P1871A Amylin (IAPP), feline TFA 98.75% Unkown
HY-114613 D-Trp-Aib Inhibitor / Unkown
HY-182304 CLR01 sodium Inhibitor / Unkown
HY-P1871 Amylin (IAPP), feline / Unkown
HY-P3926 Amylin (8-37) (human) / Unkown
HY-RS06506 IAPP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17689 Iapp Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24151 Iapp Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Iapp NCBI NCBI:3375