Sstr1 - somatostatin receptor 1 Gene

Also Known as Gpcrrna

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25033

About Sstr1

Primary_assembly 6: 75,832,530-75,836,802 forward strand.mRatBN7.2:CM026979.1

This gene has 1 transcript (splice variant), 160 orthologues, 14 paralogues and is associated with 5 phenotypes. Biased expression in Brain (RPKM 54.5) and Lung (RPKM 13.9).

Summary

Enables Somatostatin Receptor activity. Involved in several processes, including brain development; cellular response to estradiol stimulus; and spermatogenesis. Located in cytoplasm and plasma membrane. Orthologous to human SSTR1 (Somatostatin Receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Sstr1 Products (1)

mRNA Protein Name
NM_012719.2 NP_036851.1 somatostatin receptor type 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables somatostatin receptor activity IMP
IMP: Inferred from mutant phenotype
1400442 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to estradiol stimulus IEP
IEP: Inferred from expression pattern
9564833 RGD
involved in cerebellum development IEP
IEP: Inferred from expression pattern
9166718 RGD
involved in forebrain development IEP
IEP: Inferred from expression pattern
10805921 RGD
involved in response to starvation IEP
IEP: Inferred from expression pattern
7956902 RGD
involved in spermatogenesis IEP
IEP: Inferred from expression pattern
9421433 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Sstr1 Protein Structure

7tmA_SSTR1

7tmA_SSTR1: cd15970 (58 - 333)

7tmA_SSTR1

7tmA_SSTR1: cd15970 (59 - 85)

7tmA_SSTR1

7tmA_SSTR1: cd15970 (92 - 118)

7tmA_SSTR1

7tmA_SSTR1: cd15970 (129 - 159)

7tmA_SSTR1

7tmA_SSTR1: cd15970 (171 - 193)

7tmA_SSTR1

7tmA_SSTR1: cd15970 (219 - 248)

7tmA_SSTR1

7tmA_SSTR1: cd15970 (263 - 293)

7tmA_SSTR1

7tmA_SSTR1: cd15970 (301 - 326)

  • 0
  • 100
  • 200
  • 300
  • 391 a.a.
Protein Preferred Names Protein Names

somatostatin receptor type 1

  • RNGPCRRNA

  • SRIF-2

  • SS-1-R

  • SS1-R

  • SS1R

  • Somatostatin receptor subtype 1

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-105172 TT-232 Agonist 98.72% Phase 2

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P1932 Cortistatin-14 99.98% Unkown
HY-P1206 CH 275 Agonist 99.52% Unkown
HY-P1201 Cyclosomatostatin Antagonist 99.56% Unkown
HY-P4452 PRL 2915 Antagonist 99.92% Unkown
HY-P3618 Cortistatin-29 (reduced) 98.12% Unkown
HY-125382A L-797591 hydrochloride Agonist 99.81% Unkown
HY-P4469 PRL 3195 Antagonist / Unkown
HY-P2150 Cortistatin-29 (rat) / Unkown
HY-P1201A Cyclosomatostatin TFA Antagonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sstr1 NCBI NCBI:6751