L-797591 hydrochloride
Based on 1 Customer Validation
L-797591 hydrochloride is a selective sst1 agonist. L-797591 hydrochloride mimicks the effects of SRIF-14 and SRIF-28 by potently inhibiting either Forskolin (HY-15371)-stimulated or CRH-stimulated cAMP accumulation.
For research use only. We do not sell to patients.
- Purity: 99.81%
- CAS No.: 3026641-74-4
- Formula: C38H50ClN5O2
- Molecular Weight:644.29
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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SSTR1 |
L-797591 (10-7 M) hydrochloride inhibits Forskolin-stimulated cAMP accumulation in cortical neuron monolayers[1].
L-797591 (1 μM; 1 h) hydrochloride inhibits CRH-stimulated cAMP accumulation in E17-18 cortical neurons[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3026641-74-4
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Appearance Solid
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Molecular Weight 644.29
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Formula C38H50ClN5O2
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Color Off-white to light yellow
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SMILES
O=C([C@@H](CC1=C2C=CC=CC2=CC=C1)NC(N(CCC3=NC=CC=C3)CCC4=CC=CC=C4)=O)NCC(C)(CC(CCN)C)C.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 55 mg/mL (85.37 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Blake AD, et al. Somatostatin receptor subtype 1 (sst(1)) regulates intracellular 3',5'-cyclic adenosine monophosphate accumulation in rat embryonic cortical neurons: evidence with L-797,591, an sst(1)-subtype-selective nonpeptidyl agonist. Neuropharmacology. 2001;40(4):590-596. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 1.5521 mL | 7.7605 mL | 15.5210 mL | 38.8024 mL |
| 5 mM | 0.3104 mL | 1.5521 mL | 3.1042 mL | 7.7605 mL | |
| 10 mM | 0.1552 mL | 0.7760 mL | 1.5521 mL | 3.8802 mL | |
| 15 mM | 0.1035 mL | 0.5174 mL | 1.0347 mL | 2.5868 mL | |
| 20 mM | 0.0776 mL | 0.3880 mL | 0.7760 mL | 1.9401 mL | |
| 25 mM | 0.0621 mL | 0.3104 mL | 0.6208 mL | 1.5521 mL | |
| 30 mM | 0.0517 mL | 0.2587 mL | 0.5174 mL | 1.2934 mL | |
| 40 mM | 0.0388 mL | 0.1940 mL | 0.3880 mL | 0.9701 mL | |
| 50 mM | 0.0310 mL | 0.1552 mL | 0.3104 mL | 0.7760 mL | |
| 60 mM | 0.0259 mL | 0.1293 mL | 0.2587 mL | 0.6467 mL | |
| 80 mM | 0.0194 mL | 0.0970 mL | 0.1940 mL | 0.4850 mL |
L-797591 hydrochloride Related Classifications
HY-125382A Related Classifications
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