2. Gene
  3. Pgr - progesterone receptor Gene

Pgr - progesterone receptor Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 25154 | Gene type: protein coding

About Pgr

Primary_assembly 8: 6,072,673-6,131,344 forward strand.mRatBN7.2:CM026981.1

This gene has 1 transcript (splice variant), 193 orthologues, 8 paralogues and is associated with 19 phenotypes. Biased expression in Uterus (RPKM 178.1), Brain (RPKM 36.9) and 1 other tissue.

Summary

Enables several functions, including sequence-specific DNA binding activity; steroid binding activity; and steroid hormone receptor activity. Involved in several processes, including cellular response to gonadotropin stimulus; estrous cycle; and regulation of transcription, DNA-templated. Located in several cellular components, including axon terminus; dendritic spine; and perikaryon. Biomarker of endometriosis and polycystic ovary syndrome. Human ortholog(s) of this gene implicated in endometriosis; hyperprolactinemia; and obesity. Orthologous to human PGR (Progesterone Receptor). [provided by Alliance of Genome Resources, Apr 2022]

Pgr Products(1)

mRNA Protein Name
NM_022847.2 NP_074038.2 progesterone receptor

Pgr Protein Structure

Prog_receptor

Prog_receptor: pfam02161 (0 - 556)

NR_DBD_GR_PR

NR_DBD_GR_PR: cd07172 (555 - 632)

NR_LBD_PR

NR_LBD_PR: cd07074 (678 - 925)

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  • 926 a.a.
Protein Preferred Names Protein Names

progesterone receptor

PR

nuclear receptor subfamily 3 group C member 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10396 PGR Human Pre-designed siRNA Set A / Unkown
HY-RS10397 Pgr Mouse Pre-designed siRNA Set A / Unkown
HY-RS10398 Pgr Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pgr NCBI NCBI:5241
Mus musculus Pgr NCBI NCBI:18667