Bglap - bone gamma-carboxyglutamate protein Gene
Also Known as Bgp; Bgpr; Bgpra; Bglap2
Species: Rattus norvegicus
Summary
A structural constituent of bone. Involved in several processes, including osteoblast development; response to hydroxyisoflavone; and response to vitamin. Located in several cellular components, including Golgi apparatus; perikaryon; and rough endoplasmic reticulum. Used to study congenital hypothyroidism and osteoporosis. Biomarker of autosomal dominant hypocalcemia; end stage renal disease; and polycystic kidney disease. Human ortholog(s) of this gene implicated in osteoarthritis; osteoporosis; prostate cancer; rheumatoid arthritis; and vitamin K deficiency bleeding. Orthologous to human BGLAP (bone gamma-carboxyglutamate protein). [provided by Alliance of Genome Resources, Apr 2022]
Bglap Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_013414.1 | NP_038200.1 | osteocalcin preproprotein |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
osteocalcin |
|
|
Recombinant Bglap Proteins
| Cat. No. | Product Name | Accession | Purity |
|---|---|---|---|
| HY-P72104 | BGLAP Protein, Rat (GST) | P04640 (Y50-V99) | ≥ 90%, as determined by reducing SDS-PAGE. |
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-P10126 | Osteocalcin, bovine | / | Unkown | |
| HY-RS01488 | BGLAP Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS18166 | Bglap Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS24640 | Bglap Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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