Fshr - follicle stimulating hormone receptor Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25449

Summary

Enables follicle-stimulating hormone receptor activity and peptide hormone binding activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway; follicle-stimulating hormone signaling pathway; and transcytosis. Located in cell surface and endosome. Human ortholog(s) of this gene implicated in 46 XX gonadal dysgenesis; ovarian dysgenesis 1; and ovarian hyperstimulation syndrome. Orthologous to human FSHR (follicle stimulating hormone receptor). [provided by Alliance of Genome Resources, Apr 2022]

Fshr Products (1)

mRNA Protein Name
NM_199237.2 NP_954707.1 follicle-stimulating hormone receptor precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables follicle-stimulating hormone receptor activity IDA
IDA: Inferred from direct assay
2126341 RGD
enables peptide hormone binding IDA
IDA: Inferred from direct assay
16899567 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
11934883 RGD
Biological Process GO Annotation Evidence References Source
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
2126341 RGD
involved in follicle-stimulating hormone signaling pathway IDA
IDA: Inferred from direct assay
12145341 RGD
involved in response to organic cyclic compound IEP
IEP: Inferred from expression pattern
28208728 RGD
involved in transcytosis IDA
IDA: Inferred from direct assay
15050368 RGD
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
11934883 RGD
located in endosome IDA
IDA: Inferred from direct assay
12907758 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

follicle-stimulating hormone receptor

  • FSH-R

  • follitropin receptor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (12)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P4190 Fsh receptor-binding inhibitor fragment(bi-10) Antagonist 99.19% Unkown
HY-12381 ML224 Antagonist 99.18% Unkown
HY-164764 ADX61623 Inhibitor 98.84% Unkown
HY-150210 FSHR agonist 1 Agonist 99.45% Unkown
HY-160857 TOP5668 Agonist 98.07% Unkown
HY-160856 TOP5300 Agonist / Unkown
HY-182705 Org 214444-0 / Unkown
HY-P10780 RFRP-3 (mouse) 98.82% Unkown
HY-RS05124 FSHR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W673613 ADX68692 Inhibitor / Unkown
HY-RS16988 Fshr Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23431 Fshr Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fshr NCBI NCBI:2492